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Chemical Compound Review

chlorobenzoate     2-chlorobenzoate

Synonyms: CPD-256, CHEBI:28303, SBB087088, ZINC00330133, AC1N9Z5Q, ...
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Disease relevance of HSDB 6017


High impact information on HSDB 6017

  • When cat2 genes were disrupted, the growth rate in 2CB culture was reduced while that in BA culture was not [1].
  • Sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blot analysis showed that while both catechol dioxygenases (CatA1 and CatA2) were produced in BA-grown cells, CatA1 was undetectable when strain TH2 was grown on 2CB or cis,cis-muconate (CCM), an intermediate of catechol degradation [1].

Gene context of HSDB 6017

  • These results suggest that although cat2 genes are not indispensable for growth of TH2 on 2CB, they are advantageous [1].


  1. Differential expression of two catechol 1,2-dioxygenases in Burkholderia sp. strain TH2. Suzuki, K., Ichimura, A., Ogawa, N., Hasebe, A., Miyashita, K. J. Bacteriol. (2002) [Pubmed]
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