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Chemical Compound Review:

AC1L9DMW 3-[[(1S,6R)-8-hydroxy-7-oxa- 2...

Synonyms:

Ishih, A. et al., Ishih, A. et al.

Ishih, Nagata, Kobayashi, Miyase, Terada, Ishih, Miyase, Terada,

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Disease relevance of Isofebrifugine

All mice treated with the fraction containing febrifugine and isofebrifugine mixture at 1 mg/kg twice a day for 5 consecutive days survived during the experiment, and the change of mean parasitemia level showed almost the same pattern as that from mice treated with the hot-water extract of the same plant leaves [1].

High impact information on Isofebrifugine

Cytokine and antibody production was investigated during the course of resolution of primary infection in Plasmodium yoelii 17XL-infected BALB/c mice treated with a mixture of febrifugine and isofebrifugine [2].
Cytokine and antibody production during the course of resolution in Plasmodium yoelii 17XL-infected BALB/c mice treated with febrifugine and isofebrifugine mixture from leaves of Hydrangea macrophylla var. Otaksa [2].

References

Comparison of antimalarial activity of the alkaloidal fraction of Hydrangea macrophylla var. Otaksa leaves with the hot-water extract in ICR mice infected with Plasmodium yoelii 17 XL. Ishih, A., Miyase, T., Terada, M. Phytotherapy research : PTR. (2003) [Pubmed]
Cytokine and antibody production during the course of resolution in Plasmodium yoelii 17XL-infected BALB/c mice treated with febrifugine and isofebrifugine mixture from leaves of Hydrangea macrophylla var. Otaksa. Ishih, A., Nagata, T., Kobayashi, F., Miyase, T., Terada, M. Parasitol. Res. (2004) [Pubmed]

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