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Chemical Compound Review:

tartrate (2R,3R)-2,3- dihydroxybutanedioic acid

Synonyms: Tartarate, Weinsaeure, L-tartarate, Threaric acid, tartaric acid, ...

Saito, K., Willaert, R. et al., Cole, A.A. et al., Bender, K. et al., Chasseaud, L.F. et al.

Willaert, De Vuyst,

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Disease relevance of tartaric acid

The one-step bioconversion of cis-epoxysuccinate (CES) to L(+)-tartaric acid by dried Rhodococcus rhodochrous cells containing CES hydrolase activity was studied by using a continuous bioconversion process [1].

High impact information on tartaric acid

After incubation in medium containing 50 mM L(+)-tartaric acid, osteoclasts and chondroclasts were heavily stained with reaction product [2].
Transfer of 3H from D-gluconic acid, specifically labelled with 3H at C-2 or C-3 and 14C at C-1, C-2, or C-3, 4, to L(+)-tartaric acid was examined in leaves and berries of Vitis labrusca cv Delaware and in leaves of Parthenocissus quinquefolia [3].
The product of Acp-2 hydrolyzes a wide variety of phosphate monoesters and is inhibited by L(+)-tartaric acid [4].
Absorption and biotransformation of L(+)-tartaric acid in rats [5].

References

Continuous production of L(+)-tartaric acid from cis-epoxysuccinate using a membrane recycle reactor. Willaert, R., De Vuyst, L. Appl. Microbiol. Biotechnol. (2006) [Pubmed]
Tartrate-resistant acid phosphatase in bone and cartilage following decalcification and cold-embedding in plastic. Cole, A.A., Walters, L.M. J. Histochem. Cytochem. (1987) [Pubmed]
Specific transfer of 3H from D-[3-3H]gluconic acid into L-tartaric acid in vitaceous plants. Saito, K. Phytochemistry (1994) [Pubmed]
Genetic variation of an acid phosphatase (Acp-2) in the laboratory rat: possible homology with mouse AP-1 and human ACP2. Bender, K., Bissbort, S., Kuhn, A., Nagel, M., Günther, E. Biochem. Genet. (1986) [Pubmed]
Absorption and biotransformation of L(+)-tartaric acid in rats. Chasseaud, L.F., Down, W.H., Kirkpatrick, D. Experientia (1977) [Pubmed]

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