Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

BICIFADINE 1-(4-methylphenyl)-3- azabicyclo[3.1.0]hexane

Synonyms: Bicifadino, Bicifadinum, PubChem18323, SureCN38793, AGN-PC-00EOS1, ...

McArdle, P. et al., Epstein, J.W. et al., Wang, R.I. et al.

McArdle, Gilligan, Cunningham, Ryder,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of BICIFADINE

The oral analgesic efficacy of bicifadine hydrochloride in postoperative pain [1].

High impact information on BICIFADINE

The pharmaceutical compound bicifadine hydrochloride, which has been found to crystallize in two polymorphic forms, has been characterized by thermal analysis, X-ray powder diffraction (XRPD), infrared (IR) spectroscopy, and near-infrared (NIR) spectroscopy [2].

Analytical, diagnostic and therapeutic context of BICIFADINE

Bicifadine, 1-(4-methylphenyl)-3-azabicyclo[3.1.0]hexane (2b), was the most potent member of the series and is presently undergoing clinical trials in man [3].

References

The oral analgesic efficacy of bicifadine hydrochloride in postoperative pain. Wang, R.I., Johnson, R.P., Lee, J.C., Waite, E.M. Journal of clinical pharmacology. (1982) [Pubmed]
Determination of the polymorphic forms of bicifadine hydrochloride by differential scanning calorimetry-thermogravimetric analysis, X-ray powder diffraction, attenuated total reflectance-infrared spectroscopy, and attenuated total reflectance-near-infrared spectroscopy. McArdle, P., Gilligan, K., Cunningham, D., Ryder, A. Applied spectroscopy. (2005) [Pubmed]
1-Aryl-3-azabicyclo[3.1.0]hexanes, a new series of nonnarcotic analgesic agents. Epstein, J.W., Brabander, H.J., Fanshawe, W.J., Hofmann, C.M., McKenzie, T.C., Safir, S.R., Osterberg, A.C., Cosulich, D.B., Lovell, F.M. J. Med. Chem. (1981) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.