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Chemical Compound Review

AC1NSVZU     2-[4-[(5S,8S,10S,13R,17R)- 3,7,12...

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Disease relevance of Glycocholic acid

  • GCA increased responses to gastric distension in controls, whereas GCA and ethanol enhanced responses to gastric distensions in rats with gastric ulcers [1].

Chemical compound and disease context of Glycocholic acid

  • To determine whether sequentially applied stimuli interact, we determined visceromotor responses (VMR) to gastric distension, measured at baseline and 60 min after instillation of saline, glycocholic acid (GCA) or ethanol through a gastrostomy in controls and rats with gastric ulcers [1].


  1. Luminal stimuli acutely sensitize visceromotor responses to distension of the rat stomach. Lamb, K., Gebhart, G.F., Bielefeldt, K. Dig. Dis. Sci. (2007) [Pubmed]
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