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Disease relevance of Gastrostomy


Psychiatry related information on Gastrostomy


High impact information on Gastrostomy

  • All patients required parenteral nutrition or failed to thrive while receiving gastrostomy feedings [9].
  • Gastroesophageal reflux during gastrostomy feeding [10].
  • Patients received either intravenous saline as a placebo or intravenous cefazolin (1 g) 30 minutes before gastrostomy [11].
  • C57BL/6, tumor necrosis factor (TNF) type I receptor-deficient, and genetically matched wild type mice were fed via an implanted gastrostomy tube a high-fat diet for 9 weeks in the increasing amount up to 85% in excess of the standard intake [12].
  • Hexamethylene bisacetamide was administered as a 5% (w/v) solution via a nasogastric or gastrostomy tube every 4 h for 5 days, followed in 21 days by a 5-day continuous i.v. infusion at the same daily dose [13].

Chemical compound and disease context of Gastrostomy


Biological context of Gastrostomy


Anatomical context of Gastrostomy

  • In the Cox multivariate model, age, progression rate of respiratory, bulbar, and lower limb symptoms, EEDC classification, percutaneous endoscopic gastrostomy, and treatment with riluzole were significantly related to outcome [23].
  • Intrinsic factor and R binder cobalamin binding capacity (CblBC) were measured in gastric juices obtained through feeding gastrostomy tubes (FG-GJ) from six patients with relatively complete obstruction to swallowing because of surgical resections for oropharyngeal or laryngeal carcinomas [24].
  • INTERVENTIONS: Animals were randomized to receive isocaloric (160 nonprotein kcal/kg/day), or isonitrogenous (1.4 g of nitrogen/kg/day [100 mmol/kg/day]) enteral (n = 10), or parenteral nutrition (n = 11) through either a gastrostomy tube or a catheter placed in the jugular vein [25].
  • Small intestine transit time was fluoroscopically measured using barium sulfate as it passed through a gastrostomy tube on postoperative days (POD) 1, 2, and 3 [26].
  • Group 1 underwent common bile duct ligation with intestinal bile salt replacement (sodium taurocholate 100 mg/kg/day) via gastrostomy and an implantable osmotic pump (CBDL + bile salts), Group 2 underwent common bile duct ligation with normal saline replacement (CBDL + saline), and Group 3 underwent a sham operation (sham control) [27].

Associations of Gastrostomy with chemical compounds


Gene context of Gastrostomy

  • All rats received an isocaloric, isonitrogenous, polymeric diet (200 kcal/kg/day, 2 gN/kg/day) by gastrostomy and were infused with either IGF-I (2.4 mg/kg/day) or vehicle by osmotic pumps subcutaneously [33].
  • Patients with clinical evidence of GER (n = 11) had significantly lower weight gain after gastrostomy (delta WAZ, -0.32 +/- 0.26 vs. 0.03 +/- 0.39; P = 0.03) [34].
  • All cultures of gastrostomy sites were retrospectively reviewed, and 28% had MRSA [35].
  • AIM: To analyse the efficacy and acceptability of supplemental overnight feeding using a percutaneous endoscopic gastrostomy (PEG) in patients with CF [36].
  • The personal experience of one of the authors (EMB) with 774 gastrostomies during a 15-year period using this technique confirms these conclusions [37].

Analytical, diagnostic and therapeutic context of Gastrostomy


  1. Multiple antibiotic-resistant Klebsiella and Escherichia coli in nursing homes. Wiener, J., Quinn, J.P., Bradford, P.A., Goering, R.V., Nathan, C., Bush, K., Weinstein, R.A. JAMA (1999) [Pubmed]
  2. Safety and factors related to survival after percutaneous endoscopic gastrostomy in ALS. ALS Percutaneous Endoscopic Gastrostomy Study Group. Chiò, A., Finocchiaro, E., Meineri, P., Bottacchi, E., Schiffer, D. Neurology (1999) [Pubmed]
  3. Risperidone versus clozapine in the treatment of psychosis in six patients with Parkinson's disease and other akinetic-rigid syndromes. Rich, S.S., Friedman, J.H., Ott, B.R. The Journal of clinical psychiatry. (1995) [Pubmed]
  4. Methicillin-resistant Staphylococcus aureus infection of percutaneous endoscopic gastrostomy sites. Hull, M., Beane, A., Bowen, J., Settle, C. Aliment. Pharmacol. Ther. (2001) [Pubmed]
  5. Antibiotic prophylaxis in percutaneous endoscopic gastrostomy. Sturgis, T.M., Yancy, W., Cole, J.C., Proctor, D.D., Minhas, B.S., Marcuard, S.P. Am. J. Gastroenterol. (1996) [Pubmed]
  6. Relationship between CAG repeat length and late-stage outcomes in Huntington's disease. Marder, K., Sandler, S., Lechich, A., Klager, J., Albert, S.M. Neurology (2002) [Pubmed]
  7. The use of a neoprene "thumb-sock" to prevent trauma in a thumb-sucking child with intractable epilepsy. Dennison, P.J., Walton-Jones, A. Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry. (1999) [Pubmed]
  8. Case study: full thickness chemical burn of the abdomen and chest. Benmier, P., Lusthaus, S., Vardy, D., Ad-el, D., Weinberg, A., Mor, E., Neuman, A., Eldad, A., Wexler, M.R. Ostomy/wound management. (1993) [Pubmed]
  9. Intestinal motility and jejunal feeding in children with chronic intestinal pseudo-obstruction. Di Lorenzo, C., Flores, A.F., Buie, T., Hyman, P.E. Gastroenterology (1995) [Pubmed]
  10. Gastroesophageal reflux during gastrostomy feeding. Coben, R.M., Weintraub, A., DiMarino, A.J., Cohen, S. Gastroenterology (1994) [Pubmed]
  11. Antibiotic prophylaxis for percutaneous endoscopic gastrostomy. A prospective, randomized, double-blind clinical trial. Jain, N.K., Larson, D.E., Schroeder, K.W., Burton, D.D., Cannon, K.P., Thompson, R.L., DiMagno, E.P. Ann. Intern. Med. (1987) [Pubmed]
  12. Steatohepatitis induced by intragastric overfeeding in mice. Deng, Q.G., She, H., Cheng, J.H., French, S.W., Koop, D.R., Xiong, S., Tsukamoto, H. Hepatology (2005) [Pubmed]
  13. Phase I bioavailability and pharmacokinetic study of hexamethylene bisacetamide (NSC 95580) administered via nasogastric tube. Ward, F.T., Kelley, J.A., Roth, J.S., Lombardo, F.A., Weiss, R.B., Leyland-Jones, B., Chun, H.G. Cancer Res. (1991) [Pubmed]
  14. Total parenteral nutrition versus gastrostomy in the preoperative preparation of patients with carcinoma of the oesophagus. Lim, S.T., Choa, R.G., Lam, K.H., Wong, J., Ong, G.B. The British journal of surgery. (1981) [Pubmed]
  15. Forced vital capacity (FVC) as an indicator of survival and disease progression in an ALS clinic population. Czaplinski, A., Yen, A.A., Appel, S.H. J. Neurol. Neurosurg. Psychiatr. (2006) [Pubmed]
  16. A randomized study of very accelerated radiotherapy with and without amifostine in head and neck squamous cell carcinoma. Bourhis, J., De Crevoisier, R., Abdulkarim, B., Deutsch, E., Lusinchi, A., Luboinski, B., Wibault, P., Eschwege, F. Int. J. Radiat. Oncol. Biol. Phys. (2000) [Pubmed]
  17. The effect of ethanol on survival time in hemorrhagic shock in an unanesthetized swine model. Zink, B.J., Syverud, S.A., Dronen, S.C., Barsan, W.G., Van Ligten, P., Timerding, B.L. Annals of emergency medicine. (1988) [Pubmed]
  18. Effects of increased beta 2-agonist dose in tumor-bearing animals. Stallion, A., Foley-Nelson, T., Chance, W.T., Fischer, J.E. Nutrition and cancer. (1993) [Pubmed]
  19. Clonidine improves postprandial baroreflex control in familial dysautonomia. Marthol, H., Tutaj, M., Brys, M., Brown, C.M., Hecht, M.J., Berlin, D., Axelrod, F.B., Hilz, M.J. Eur. J. Clin. Invest. (2003) [Pubmed]
  20. Short- and long-term effects of combined pre- and postnatal ethanol exposure (three trimester equivalency) on the development of myelin and axons in rat optic nerve. Phillips, D.E., Krueger, S.K., Rydquist, J.E. Int. J. Dev. Neurosci. (1991) [Pubmed]
  21. Prenatal ethanol exposure during the last third of gestation in rat reduces hippocampal NMDA agonist binding site density in 45-day-old offspring. Savage, D.D., Queen, S.A., Sanchez, C.F., Paxton, L.L., Mahoney, J.C., Goodlett, C.R., West, J.R. Alcohol (1992) [Pubmed]
  22. Early and late complications of pylorus-preserving pancreatoduodenectomy in Japan 1998. Yamaguchi, K., Tanaka, M., Chijiiwa, K., Nagakawa, T., Imamura, M., Takada, T. Journal of hepato-biliary-pancreatic surgery. (1999) [Pubmed]
  23. Early symptom progression rate is related to ALS outcome: a prospective population-based study. Chiò, A., Mora, G., Leone, M., Mazzini, L., Cocito, D., Giordana, M.T., Bottacchi, E., Mutani, R. Neurology (2002) [Pubmed]
  24. Rapid collection of human intrinsic factor uncontaminated with cobalophilin (R binder). Herzlich, B., Herbert, V. Am. J. Gastroenterol. (1986) [Pubmed]
  25. Recovery from ischemic acute renal failure is improved with enteral compared with parenteral nutrition. Mouser, J.F., Hak, E.B., Kuhl, D.A., Dickerson, R.N., Gaber, L.W., Hak, L.J. Crit. Care Med. (1997) [Pubmed]
  26. Improvement of intestinal motility using S-methylisothiourea in postoperative ileus. Uenoyama, S., Kobayashi, T., Takeuchi, Y., Yamashita, K., Koide, Y., Kazui, T. Am. J. Surg. (2004) [Pubmed]
  27. Obstructive jaundice alters Kupffer cell function independent of bacterial translocation. Sheen-Chen, S.M., Chau, P., Harris, H.W. J. Surg. Res. (1998) [Pubmed]
  28. Percutaneous endoscopic gastrostomy. Initial placement by single endoscopic technique and long-term follow-up. Grant, J.P. Ann. Surg. (1993) [Pubmed]
  29. Management of acid-related disorders in patients with dysphagia. Howden, C.W. Am. J. Med. (2004) [Pubmed]
  30. Nursing home residents and Enterobacteriaceae resistant to third-generation cephalosporins. Sandoval, C., Walter, S.D., McGeer, A., Simor, A.E., Bradley, S.F., Moss, L.M., Loeb, M.B. Emerging Infect. Dis. (2004) [Pubmed]
  31. Large-scale gene profiling of the liver in a mouse model of chronic, intragastric ethanol infusion. Deaciuc, I.V., Doherty, D.E., Burikhanov, R., Lee, E.Y., Stromberg, A.J., Peng, X., de Villiers, W.J. J. Hepatol. (2004) [Pubmed]
  32. Ciprofloxacin absorption is impaired in patients given enteral feedings orally and via gastrostomy and jejunostomy tubes. Healy, D.P., Brodbeck, M.C., Clendening, C.E. Antimicrob. Agents Chemother. (1996) [Pubmed]
  33. Insulin-like growth factor-I improves mucosal structure and function in transplanted rat small intestine. Zhang, W., Frankel, W.L., Adamson, W.T., Roth, J.A., Mantell, M.P., Bain, A., Ziegler, T.R., Smith, R.J., Rombeau, J.L. Transplantation (1995) [Pubmed]
  34. Factors affecting clinical outcome in gastrostomy-fed children with cystic fibrosis. Oliver, M.R., Heine, R.G., Ng, C.H., Volders, E., Olinsky, A. Pediatr. Pulmonol. (2004) [Pubmed]
  35. Percutaneous endoscopic gastrostomy as an unrecognized source of methicillin-resistant Staphylococcus aureus colonization. Nunley, D., Berk, S.L. Am. J. Gastroenterol. (1992) [Pubmed]
  36. Percutaneous endoscopic gastrostomy feeding in patients with cystic fibrosis. Williams, S.G., Ashworth, F., McAlweenie, A., Poole, S., Hodson, M.E., Westaby, D. Gut (1999) [Pubmed]
  37. Experience with a modified Witzel gastrostomy without gastropexy. Johnston, W.D., Lopez, M.J., Kraybill, W.G., Bricker, E.M. Ann. Surg. (1982) [Pubmed]
  38. Protective antireflux operation with feeding gastrostomy. Experience with children. Jolley, S.G., Smith, E.I., Tunell, W.P. Ann. Surg. (1985) [Pubmed]
  39. Symptomatic gastroesophageal reflux following gastrostomy in neurologically impaired patients. Mollitt, D.L., Golladay, E.S., Seibert, J.J. Pediatrics (1985) [Pubmed]
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