Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CID6328137 aluminum; octadecanoic acid; dihydrate

Synonyms:

This record was replaced with 5281.

Schultze, W.D. et al., Schultze, W.D. et al., Smith, A.M. et al., Brown, S.T.

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Disease relevance of oleic acid

Additional dose-ranging studies have been performed in patients with gastric cancer using 100- and 200-microg doses of G17-DT formulated without adjuvant and the emulsifier aluminum monostearate [1].

High impact information on oleic acid

An experimental product incorporating 500,000 IU of procaine penicillin G and 600 mg of sodium novobiocin in 2% aluminum monostearate-peanut oil gel (10-ml dose) was used to treat all quarters of 56 cows which were infected in at least 1 quarter at time of final mild-out at end of lactation [2].
An experimental product incorporating 500,000 IU of procaine penicillin G and 600 mg of sodium novobiocin in 2% aluminum monostearate-peanut oil gel (10-ml dose) was infused after the final milk-out at end of lactation into all 4 mammary quarters of 56 cows that were infected in at least 1 quarter [3].
Although both aqueous penicillin G and procaine penicillin G in oil with aluminum monostearate (PAM) appear effective, these are not practical penicillin forms [4].

References

Phase I/II study of G17-DT, an anti-gastrin immunogen, in advanced colorectal cancer. Smith, A.M., Justin, T., Michaeli, D., Watson, S.A. Clin. Cancer Res. (2000) [Pubmed]
Nonlactating-cow therapy with a formulation of penicillin and novobiocin: therapeutic and prophylactic effects. Schultze, W.D., Mercer, H.D. Am. J. Vet. Res. (1976) [Pubmed]
Nonlactating-cow therapy with a formulation of penicillin and novobiocin: mammary irritation and residues. Schultze, W.D., Mercer, H.D. Am. J. Vet. Res. (1976) [Pubmed]
Treatment of secondary syphilis. Brown, S.T. Journal of the American Venereal Disease Association. (1976) [Pubmed]

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