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Chemical Compound Review

crotonol     (E)-but-2-en-1-ol

Synonyms: Krotylalkohol, PubChem21075, CHEMBL118459, C86006_ALDRICH, Crotyl alcohol, ...
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Disease relevance of trans-Crotonyl Alcohol

  • To facilitate study of the mechanisms underlying CA toxicity, we explored the possibility that it can be formed enzymatically from an unsaturated precursor, crotyl alcohol [1].

High impact information on trans-Crotonyl Alcohol


  1. Oxidative bioactivation of crotyl alcohol to the toxic endogenous aldehyde crotonaldehyde: association of protein carbonylation with toxicity in mouse hepatocytes. Fontaine, F.R., Dunlop, R.A., Petersen, D.R., Burcham, P.C. Chem. Res. Toxicol. (2002) [Pubmed]
  2. Epoxidation of olefins by cytochrome P450: evidence from site-specific mutagenesis for hydroperoxo-iron as an electrophilic oxidant. Vaz, A.D., McGinnity, D.F., Coon, M.J. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  3. Effect of structure of the redox molecular sieve TS-1 on the oxidation of phenol, crotyl alcohol and norbornylene. Kerton, O.J., McMorn, P., Bethell, D., King, F., Hancock, F., Burrows, A., Kiely, C.J., Ellwood, S., Hutchings, G. Physical chemistry chemical physics : PCCP. (2005) [Pubmed]
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