Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Affinin (2E,4E,8E)-N-butan-2-yldeca- 2,4,8-trienamide

Synonyms: Spilanthol, AC1O5GYR, LS-59410, N-Isobutyl-2E-decenamide, 2,6,8-DECATRIENAMIDE, N-ISOBUTYL-, (E,E,Z)-

Molina-Torres, J. et al., Molina-Torres, J. et al., Ramírez-Chávez, E. et al.

Molina-Torres, Salazar-Cabrera, Armenta-Salinas, Ramírez-Chávez,

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Disease relevance of Affinin

Affinin had a definite negative effect on the growth of E. coli and B. subtilis, but E. carotovora carotovora was not sensitive to the highest dose of affinin assayed [1].

High impact information on Affinin

We found that treatments with affinin in the range of 10(-6) to 10(-4) m alter shoot and root biomass production [2].
The bioactive amides affinin and capsaicin isolated respectively from Heliopsis longipes roots and Capsicum spp fruits, were assayed for activity against Escherichia coli, Pseudomonas solanacearum, Bacillus subtilis and Saccharomyces cerevisicae suspension cultures [3].

References

Fungistatic and bacteriostatic activities of alkamides from Heliopsis longipes roots: affinin and reduced amides. Molina-Torres, J., Salazar-Cabrera, C.J., Armenta-Salinas, C., Ramírez-Chávez, E. J. Agric. Food Chem. (2004) [Pubmed]
Alkamides isolated from plants promote growth and alter root development in Arabidopsis. Ramírez-Chávez, E., López-Bucio, J., Herrera-Estrella, L., Molina-Torres, J. Plant Physiol. (2004) [Pubmed]
Antimicrobial properties of alkamides present in flavouring plants traditionally used in Mesoamerica: affinin and capsaicin. Molina-Torres, J., García-Chávez, A., Ramírez-Chávez, E. Journal of ethnopharmacology. (1999) [Pubmed]

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