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Chemical Compound Review:

Furanace [6-[(E)-2-(5-nitro-2- furyl)ethenyl]pyridin...

Synonyms: Furpirinol, Furpyrinol, Nifurpirinol, Nifurpirinolum, Furanace-10, ...

Kimura, I. et al., Ferguson, H.W. et al., Tamse, C.T. et al., Nakamura, Y. et al.

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Disease relevance of Furanace

Mutagenicity of nifurpirinol (P-7138) in Escherichia coli WP2 and Salmonella typhimurium TA100 [1].
The 40 surviving fish, including some sick ones, were treated with nifurpirinol at the rate of 0.2 mg/L and 5 mg/kg of body weight, by means of a bath and a feed medication, respectively [2].
Acute toxicity of nifurpirinol, a fish chemotherapeutant, to milkfish (Chanos chanos) fingerlings [3].
During the course of experimental studies on the chromatophoromas using tank-reared nibe, we found that nifurpirinol (NP), a drug used for the treatment of fish diseases, might also induce the chromatophoromas in the fish, as well as N-methyl-N'-nitro-N-nitrosoguanidine and 7,12-dimethylbenz[alpha]anthracene [4].

References

Mutagenicity of nifurpirinol (P-7138) in Escherichia coli WP2 and Salmonella typhimurium TA100. Nakamura, Y., Fukushima, H., Tomita, I., Kimura, I. Mutat. Res. (1982) [Pubmed]
Disseminated hexamitiasis in Siamese fighting fish. Ferguson, H.W., Moccia, R.D. J. Am. Vet. Med. Assoc. (1980) [Pubmed]
Acute toxicity of nifurpirinol, a fish chemotherapeutant, to milkfish (Chanos chanos) fingerlings. Tamse, C.T., Gacutan, R.Q. Bulletin of environmental contamination and toxicology. (1994) [Pubmed]
Correlation of epizootiological observations with experimental data: chemical induction of chromatophoromas in the croaker, Nibea mitsukurii. Kimura, I., Taniguchi, N., Kumai, H., Tomita, I., Kinae, N., Yoshizaki, K., Ito, M., Ishikawa, T. National Cancer Institute monograph. (1984) [Pubmed]

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