Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AC1O5RSE N-[(E)-11-[(12Z,14Z)-3,9- dihydroxy-11,17...

Synonyms: 150346-23-9

Sasse, F. et al., Gronewold, T.M. et al.

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Disease relevance of Rhizopodin

A new cytostatic compound, rhizopodin, was isolated from the culture broth of the myxobacterium, Myxococcus stipitatus [1].

High impact information on Rhizopodin

When 100 nM rhizopodin was added to PtK2 cells, the stress fibers began to decay after just 10 min and had disappeared completely after about 3 h [2].
Rhizopodin suppresses bleb formation in K-562 cells, and therefore could act by interacting with protein phosphorylation [1].

Analytical, diagnostic and therapeutic context of Rhizopodin

Rhizopodin, a new compound from Myxococcus stipitatus (myxobacteria) causes formation of rhizopodia-like structures in animal cell cultures. Production, isolation, physico-chemical and biological properties [1].

References

Rhizopodin, a new compound from Myxococcus stipitatus (myxobacteria) causes formation of rhizopodia-like structures in animal cell cultures. Production, isolation, physico-chemical and biological properties. Sasse, F., Steinmetz, H., Höfle, G., Reichenbach, H. J. Antibiot. (1993) [Pubmed]
Effects of rhizopodin and latrunculin B on the morphology and on the actin cytoskeleton of mammalian cells. Gronewold, T.M., Sasse, F., Lünsdorf, H., Reichenbach, H. Cell Tissue Res. (1999) [Pubmed]

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