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Chemical Compound Review:

SureCN1999862 1,4-dioxane-2,5-dione; oxepan-2-one

Synonyms: AC1L238S, D05540, 41706-81-4, Poliglecaprone 25, Poliglecaprone 90, ...

Andrade, M.G. et al., Sylvestre, A. et al., Shapiro, A.J. et al., Bernstein, R.M. et al., Runk, A. et al.

Bernstein, Rassman, Rashid,

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Disease relevance of Poliglecaprone 25

Around the poliglecaprone 25, a diffused infiltration of a few mononuclear cells and fibrosis was recorded and formation of craters was observed on its surface [1].

High impact information on Poliglecaprone 25

This paper aimed to study rat subcutaneous tissue reaction to irradiated polyglactin 910, polydioxanone, poliglecaprone 25 and chromic gut and its correlation with the ultra-structural alterations the materials undergo [1].
The purpose of this study was to compare postoperative wound healing in canine ovariohysterectomy following the use of an absorbable monofilament poliglecaprone 25 suture in 2 different skin closure techniques, the buried continuous subcuticular (BCS) suture pattern and the simple interrupted (SI) suture pattern [2].

Analytical, diagnostic and therapeutic context of Poliglecaprone 25

CONCLUSION: Poliglecaprone 25 is a strong synthetic, absorbable, monofilament suture with low tissue reactivity that can be used in hair transplantation to close the donor wound with a single, running cutaneous stitch [3].
Segments of fresh porcine skin measuring 3.5 x 10 cm were approximated by one of four methods: 1) 2-octyl cyanoacrylate glue, 2) surgical staples, 3) 0.5 inch Steri-Strips, and 4) interrupted 4-0 poliglecaprone 25 sutures in a subcuticular fashion [4].
OBJECTIVE: To use poliglecaprone 25 for all ligations and closure in routine feline ovariohysterectomies and evaluate maintenance of tissue approximation and tissue reaction to the suture [5].

References

Tissue reaction and surface morphology of absorbable sutures after in vivo exposure. Andrade, M.G., Weissman, R., Reis, S.R. Journal of materials science. Materials in medicine. (2006) [Pubmed]
A comparison of 2 different suture patterns for skin closure of canine ovariohysterectomy. Sylvestre, A., Wilson, J., Hare, J. Can. Vet. J. (2002) [Pubmed]
A new suture for hair transplantation: poliglecaprone 25. Bernstein, R.M., Rassman, W.R., Rashid, N. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]. (2001) [Pubmed]
Tensile strength of wound closure with cyanoacrylate glue. Shapiro, A.J., Dinsmore, R.C., North, J.H. The American surgeon. (2001) [Pubmed]
Tissue reactivity to poliglecaprone 25 in the feline linea alba. Runk, A., Allen, S.W., Mahaffey, E.A. Veterinary surgery : VS : the official journal of the American College of Veterinary Surgeons. (1999) [Pubmed]

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