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Chemical Compound Review:

AMTDA071 4-phenylbenzoic acid

Synonyms: PubChem10321, SureCN38562, AGN-PC-00G6QC, CHEMBL107057, B34729_ALDRICH, ...

Nanbo, T., Nanbo, T. et al., Nanbo, T., Kawahara, M. et al., Nanbo, T., et al.

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High impact information on NSC23040

A pharmacokinetic model of the maternal-fetal amniotic fluid system was designed to permit calculation of clearances from the steady-state concentrations of p-phenylbenzoic acid (PPBA) during infusion of PPBA into the maternal vein and the amniotic fluid of pregnant rats on the 16th to the 21st day of gestation [1].
UDPGT activity for phenol and p-phenylbenzoic acid, and phospholipid content and fluidity increased with day of gestation [2].
Following oral administration of p-phenylbenzoic acid to the rats for 7 days, the decrease of the triglyceride synthesized from [14C]oleic acid was observed in the adipose tissue [3].
Pharmacokinetics of p-phenylbenzoic acid in near-term fetus of the rat [4].
Disposition of p-phenylbenzoic acid (PPBA) in the pregnant Wistar rat (for both mother and fetuses) was predicted by using a physiologically based pharmacokinetic model [5].

Associations of NSC23040 with other chemical compounds

Developmental change in clearance of glucuronide of p-phenylbenzoic acid from in vitro kinetic parameters and its correlation with clearance from in vivo in fetus of rat [6].

References

Pharmacokinetics of clearance in the maternal-fetal amniotic fluid system of the rat. Nanbo, T. Toxicol. Appl. Pharmacol. (1988) [Pubmed]
Developmental changes in hepatic microsomal interactions between UDP-glucuronyltransferase and phospholipid in the rat fetus. Nanbo, T. Reprod. Toxicol. (1998) [Pubmed]
The relationship between the effect of biphenylcarboxylic acid analogs on glyceride synthesis and conformation. Nanbo, T., Taga, T., Machida, K. Chem. Biol. Interact. (1993) [Pubmed]
Pharmacokinetics of p-phenylbenzoic acid in near-term fetus of the rat. Nanbo, T. Chem. Pharm. Bull. (1983) [Pubmed]
Physiologically based pharmacokinetic prediction of p-phenylbenzoic acid disposition in the pregnant rat. Kawahara, M., Nanbo, T., Tsuji, A. Biopharmaceutics & drug disposition. (1998) [Pubmed]
Developmental change in clearance of glucuronide of p-phenylbenzoic acid from in vitro kinetic parameters and its correlation with clearance from in vivo in fetus of rat. Nanbo, T. J. Pharmacobio-dyn. (1983) [Pubmed]

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