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Chemical Compound Review

Nikethan     ethyl pyridine-3-carboxylate

Synonyms: Nikithan, Ignicut, Ignocut, Mucotherm, Nicaethan, ...
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High impact information on Ignicut


Analytical, diagnostic and therapeutic context of Ignicut

  • The objective of this research was to compare the characteristics of skin permeation and metabolism of ethyl nicotinate (EN) among humans and several animal models [4].


  1. Utility of a three-dimensional cultured human skin model as a tool to evaluate the simultaneous diffusion and metabolism of ethyl nicotinate in skin. Sugibayashi, K., Hayashi, T., Matsumoto, K., Hasegawa, T. Drug Metab. Pharmacokinet. (2004) [Pubmed]
  2. Age dependency of esterase activity in rat and human keratinocytes. Ngawhirunpat, T., Kawakami, N., Hatanaka, T., Kawakami, J., Adachi, I. Biol. Pharm. Bull. (2003) [Pubmed]
  3. Simultaneous transport and metabolism of nicotinic acid derivatives in hairless mouse skin. Rittirod, T., Hatanaka, T., Kagami, N., Katayama, K., Koizumi, T. Biol. Pharm. Bull. (1999) [Pubmed]
  4. Species difference in simultaneous transport and metabolism of ethyl nicotinate in skin. Rittirod, T., Hatanaka, T., Uraki, A., Hino, K., Katayama, K., Koizumi, T. International journal of pharmaceutics. (1999) [Pubmed]
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