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MeSH Review

Mice, Inbred HRS

 
 
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Disease relevance of Mice, Inbred HRS

 

High impact information on Mice, Inbred HRS

  • Tumour promotion by TCDD in skin of HRS/J hairless mice [6].
  • The most striking defect is brittle hair resulting in alopecia (hairless mice) [7].
  • Using a hairless mouse model, we have demonstrated that testosterone reduction stimulates the healing response not through hair follicle epithelial/mesenchymal cell proliferation, but directly via effects on wound cell populations [8].
  • We show here that topical application of TNF after experimental injury to the SC of hairless mice (hr(-/-)) enhances barrier repair [9].
  • Because tumor necrosis factor (TNF) and other cytokines are known products of keratinocytes and have been shown to modulate lipid and DNA synthesis in other systems, their levels were examined in two acute models and one chronic model of barrier perturbation in hairless mice [10].
 

Chemical compound and disease context of Mice, Inbred HRS

 

Biological context of Mice, Inbred HRS

 

Anatomical context of Mice, Inbred HRS

 

Associations of Mice, Inbred HRS with chemical compounds

 

Gene context of Mice, Inbred HRS

 

Analytical, diagnostic and therapeutic context of Mice, Inbred HRS

References

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  6. Tumour promotion by TCDD in skin of HRS/J hairless mice. Poland, A., Palen, D., Glover, E. Nature (1982) [Pubmed]
  7. Hoxc13 mutant mice lack external hair. Godwin, A.R., Capecchi, M.R. Genes Dev. (1998) [Pubmed]
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  13. Latent herpes simplex virus infections in sensory ganglia of hairless mice prevented by acycloguanosine. Klein, R.J., Friedman-Kien, A.E., DeStefano, E. Antimicrob. Agents Chemother. (1979) [Pubmed]
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  16. Modulations of critical cell cycle regulatory events during chemoprevention of ultraviolet B-mediated responses by resveratrol in SKH-1 hairless mouse skin. Reagan-Shaw, S., Afaq, F., Aziz, M.H., Ahmad, N. Oncogene (2004) [Pubmed]
  17. Suppression of UVB-induced phosphorylation of mitogen-activated protein kinases and nuclear factor kappa B by green tea polyphenol in SKH-1 hairless mice. Afaq, F., Ahmad, N., Mukhtar, H. Oncogene (2003) [Pubmed]
  18. Activation of telomerase and its association with G1-phase of the cell cycle during UVB-induced skin tumorigenesis in SKH-1 hairless mouse. Balasubramanian, S., Kim, K.H., Ahmad, N., Mukhtar, H. Oncogene (1999) [Pubmed]
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  21. Topical tretinoin increases the tropoelastin and fibronectin content of photoaged hairless mouse skin. Schwartz, E., Kligman, L.H. J. Invest. Dermatol. (1995) [Pubmed]
  22. Cytochrome P-450 dependent deethylase activity in rat and hairless mouse skin microsomes. Moloney, S.J., Fromson, J.M., Bridges, J.W. Biochem. Pharmacol. (1982) [Pubmed]
  23. Effects of all-trans-retinoic acid on the dermis of hairless mice. Kligman, L.H. J. Am. Acad. Dermatol. (1986) [Pubmed]
  24. Ultraviolet B radiation increases hairless mouse mast cells in a dose-dependent manner and alters distribution of UV-induced mast cell growth factor. Kligman, L.H., Murphy, G.F. Photochem. Photobiol. (1996) [Pubmed]
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  31. A parathyroid hormone antagonist stimulates epidermal proliferation and hair growth in mice. Holick, M.F., Ray, S., Chen, T.C., Tian, X., Persons, K.S. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
  32. Cyclooxygenase-1 deletion enhances apoptosis but does not protect against ultraviolet light-induced tumors. Pentland, A.P., Scott, G., VanBuskirk, J., Tanck, C., LaRossa, G., Brouxhon, S. Cancer Res. (2004) [Pubmed]
  33. Frequent p53 alterations but low incidence of ras mutations in UV-B-induced skin tumors of hairless mice. van Kranen, H.J., de Gruijl, F.R., de Vries, A., Sontag, Y., Wester, P.W., Senden, H.C., Rozemuller, E., van Kreijl, C.F. Carcinogenesis (1995) [Pubmed]
  34. Peroxisome-proliferator-activated receptor (PPAR)-gamma activation stimulates keratinocyte differentiation. Mao-Qiang, M., Fowler, A.J., Schmuth, M., Lau, P., Chang, S., Brown, B.E., Moser, A.H., Michalik, L., Desvergne, B., Wahli, W., Li, M., Metzger, D., Chambon, P.H., Elias, P.M., Feingold, K.R. J. Invest. Dermatol. (2004) [Pubmed]
  35. Basis for improved permeability barrier homeostasis induced by PPAR and LXR activators: liposensors stimulate lipid synthesis, lamellar body secretion, and post-secretory lipid processing. Man, M.Q., Choi, E.H., Schmuth, M., Crumrine, D., Uchida, Y., Elias, P.M., Holleran, W.M., Feingold, K.R. J. Invest. Dermatol. (2006) [Pubmed]
  36. Enhancement of antioxidant and phase II enzymes by oral feeding of green tea polyphenols in drinking water to SKH-1 hairless mice: possible role in cancer chemoprevention. Khan, S.G., Katiyar, S.K., Agarwal, R., Mukhtar, H. Cancer Res. (1992) [Pubmed]
  37. Comparative ultrastructure and cytochemistry of epidermal responses to tape stripping, ethanol and vitamin A acid in hairless mice. Brown, W.R., Habowsky, J.E. J. Invest. Dermatol. (1979) [Pubmed]
  38. Ultraviolet B-induced apoptosis of keratinocytes in murine skin is reduced by mild local hyperthermia. Kane, K.S., Maytin, E.V. J. Invest. Dermatol. (1995) [Pubmed]
  39. Repair of pyrimidine(6-4)pyrimidone photoproducts in mouse skin. Mitchell, D.L., Cleaver, J.E., Epstein, J.H. J. Invest. Dermatol. (1990) [Pubmed]
  40. Induction, repair and accumulation of thymine dimers in the skin of UV-B-irradiated hairless mice. Vink, A.A., Berg, R.J., de Gruijl, F.R., Roza, L., Baan, R.A. Carcinogenesis (1991) [Pubmed]
 
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