Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

Vexibinol (2S)-2-(2,4-dihydroxyphenyl)- 5,7-dihydroxy...

Synonyms: CHEMBL243148, AG-K-38265, SureCN2228023, CHEBI:50209, KST-1A0157, ...

Yamahara, J. et al., Yamahara, J. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Vexibinol

The inhibitory effect of vexibinol, one of the flavanols found in Sophora, on gastric ulcers induced by HCl-ethanol has been reported previously [1].

High impact information on Vexibinol

These results suggest that vexibinol has not only gastric mucosal protective action but also an inhibitory effect on the secretion of gastric acids [1].
Results suggest that oral administration of 50 mg/kg of vexibinol, a flavanol found in the extract, inhibited ulceration more effectively than spizofurone at 100 mg/kg [2].

References

The antiulcer action of sophora and the active constituent in Sophora. II. The antiulcer action of vexibinol. Yamahara, J., Mochizuki, M., Chisaka, T., Fujimura, H., Tamai, Y. Chem. Pharm. Bull. (1990) [Pubmed]
Antiulcer action of Sophora flavescens root and an active constituent. I. Yamahara, J., Mochizuki, M., Fujimura, H., Takaishi, Y., Yoshida, M., Tomimatsu, T., Tamai, Y. Journal of ethnopharmacology. (1990) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share