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Chemical Compound Review

Fluorenol     9H-fluoren-9-ol

Synonyms: Fluoren-9-ol, CHEMBL571548, SureCN216862, NSC-5320, ACMC-1C7AR, ...
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Disease relevance of NSC5320


High impact information on NSC5320

  • The SmC phase formed by the fluorenol mesogens is more stable and has a wider temperature range than that formed by the fluorenone mesogens, which may be ascribed to intermolecular hydrogen bonding according to variable-temperature FT-IR measurements [2].
  • The C11 fluorenol mesogens (R,R)-3d and (S,R)-3d were obtained in diastereomerically pure form and gave reduced polarization (Po) values of +106 and +183 nC/cm2, respectively, at 10 K below the SmA*-SmC* phase transition temperature [2].
  • Since strain F101 is not able to grow with fluorenone, two different pathways of fluorene biodegradation are suggested: one supports cell growth and produces 3,4-dihydrocoumarin as an intermediate and probably the unidentified metabolite, and the other produces 9-fluorenol and 9H-fluoren-9-one and appears to be a dead-end route [3].


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