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Chemical Compound Review

IPTG     (2R,3R,4S,5R,6S)-2- (hydroxymethyl)-6...

Synonyms: PubChem9901, AC1LCVOH, SureCN25476, ARK037, CHEBI:61448, ...
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High impact information on ISOPROPYL THIOGALACTOSIDE


Chemical compound and disease context of ISOPROPYL THIOGALACTOSIDE






Associations of ISOPROPYL THIOGALACTOSIDE with other chemical compounds

  • In medium containing methotrexate but no IPTG, the clones were unable to grow in soft agar, indicating that methotrexate resistance due to gene amplification is separable from transformation [26].
  • Following transcriptional induction with IPTG or galactose, subcellular fractions were prepared and analyzed immunochemically and catalytically [27].
  • In the absence of an inducer (allolactose or IPTG) this strain, DH1 lackan , cannot grow on kanamycin-containing media due to the repression of kan expression by LacI protein binding to lac O/P [28].
  • Nutrient starvation experiments and the use of relA spoT mutant strains, IPTG-regulated overproduction of ppGpp and lacZ fusions revealed that the stringent response alarmone guanosine 3',5'-bispyrophosphate (ppGpp) is the main positive effector of Cka synthesis [29].
  • In contrast, in these cells, IPTG-dependent induction of p14ARF, which sequesters MDM2 away from p53, does not lead to detectable phosphorylation of any of the five N-terminal serine residues tested (6, 9, 15, 20, 37) [30].



Analytical, diagnostic and therapeutic context of ISOPROPYL THIOGALACTOSIDE


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