Disease relevance of Ronicol

• Fibrinolytic activity and the effects of beta-pyridylcarbinol (Ronicol) in patients with arteriosclerosis obliterans [1].
• In the canine myocardial infarction model employed it was observed that the duration of the anti-ischaemic effect of Ronicol (1 mg/kg iv.) is about 120 minutes [2].

High impact information on Ronicol

• Derivatization using 3-pyridylcarbinol coupled with liquid chromatography electrospray ionization tandem mass spectrometry (LC/MS/MS) was used to characterize a novel Phase II metabolite of the nephrotoxic agricultural fungicide, N-(3,5-dichlorophenyl)succinimide (NDPS) [3].
• Effects of the lipolysis inhibiting agent beta-pyridylcarbinol (Ronicol) in acute myocardial ischaemia [2].
• The cardiac effects of Ronicol were therefore studied on a self-control, 'single-vessel' coronary artery ligature dog model [2].
• Thermography for studying nicotinyl alcohol tartrate [4].

Anatomical context of Ronicol

• Twenty-one patients with arteriosclerosis obliterans of lower extremities were treated with beta-pyridylcarbinol (Ronicol) for five weeks [1].

Analytical, diagnostic and therapeutic context of Ronicol

• Following the control ligation, a stabilization period and Ronicol infusion (1 mg/kg iv. during 10 minutes), the LAD was repeatedly ligated [2].

References