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Chemical Compound Review:

Bibenzylamine N-benzyl-1-phenyl-methanamine

Synonyms: Dibenzylamine, bisbenzylamine, DIBENZYL-AMINE, PubChem7523, SureCN1654, ...

Doepner, B. et al., Beckett, A.H. et al., Calvo, M.B. et al., Calvo, M.B. et al., Ayala, N.L. et al.

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High impact information on NSC 4811

It is concluded that DBA is a novel blocker of the voltage-dependent K+ current in mouse cardiac myocytes which preferentially affects the current component generating the slow recovery from inactivation [1].
Kinetic study on the nitrosation of dibenzylamine in a model system [2].
A study of the in vitro metabolism of dibenzylamine with fortified rabbit liver 9000 g supernatant fractions has shown that N-oxidation is the major metabolic process [3].
Pharmacokinetics of dibenzylamine administered in a sustained drug delivery system with cefazolin [4].

Analytical, diagnostic and therapeutic context of NSC 4811

Determination of low concentrations of dibenzylamine in human plasma and urine by gas chromatography with a nitrogen-phosphorus detector [5].

References

Dibenzylamine--a novel blocker of the voltage-dependent K+ current in myocardial mouse cells. Doepner, B., Koopmann, R., Knopp, A., Hirche, H., Benndorf, K. Naunyn Schmiedebergs Arch. Pharmacol. (2001) [Pubmed]
Kinetic study on the nitrosation of dibenzylamine in a model system. Ayala, N.L., Fiddler, W., Gates, R.A., Pensabene, J.W. Food Chem. Toxicol. (1994) [Pubmed]
The metabolism of dibenzylamine: identification of NN-dibenzylhydroxylamine as the major in vitro metabolic product from rabbit fortified hepatic homogenates. Beckett, A.H., Coutts, R.T., Gibson, G.G. J. Pharm. Pharmacol. (1975) [Pubmed]
Pharmacokinetics of dibenzylamine administered in a sustained drug delivery system with cefazolin. Calvo, M.B., Pedraz, J.L., Domínguez-Gil, A. Biopharmaceutics & drug disposition. (1990) [Pubmed]
Determination of low concentrations of dibenzylamine in human plasma and urine by gas chromatography with a nitrogen-phosphorus detector. Calvo, M.B., Pedraz, J.L., Domínguez-Gil, A. J. Chromatogr. (1989) [Pubmed]

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