Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AG-J-68685 5-undecyloxolan-2-one

Synonyms: SureCN7054931, AC1L1PJL, CTK2H1000, AR-1G9589, AC1Q6HG5, ...

Wang, B.H. et al., Ceccorulli, G. et al., Thompson, C.J. et al.

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High impact information on AI3-30956

Random copolymers were prepared by Candida antarctica lipase B (Novozyme-435) catalyzed copolymerization of omega-pentadecalactone (PDL) with epsilon-caprolactone (CL) [1].
However, laurylgallate and 15-pentadecanolide are also potent and selective inhibitors of cAK (IC50 values 1.5 and 20 microM, respectively) although the structures of both of these compounds involve a large non-polar portion associated with only one polar region [2].

Analytical, diagnostic and therapeutic context of AI3-30956

Enzymatic synthesis and evaluation of new novel omega-pentadecalactone polymers for the production of biodegradable microspheres [3].

References

Cocrystallization of random copolymers of omega-pentadecalactone and epsilon-caprolactone synthesized by lipase catalysis. Ceccorulli, G., Scandola, M., Kumar, A., Kalra, B., Gross, R.A. Biomacromolecules (2005) [Pubmed]
Selective inhibition of cyclic AMP-dependent protein kinase by amphiphilic triterpenoids and related compounds. Wang, B.H., Polya, G.M. Phytochemistry (1996) [Pubmed]
Enzymatic synthesis and evaluation of new novel omega-pentadecalactone polymers for the production of biodegradable microspheres. Thompson, C.J., Hansford, D., Higgins, S., Hutcheon, G.A., Rostron, C., Munday, D.L. Journal of microencapsulation. (2006) [Pubmed]

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