Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

SureCN177687 1-[(3S,8R,9S,10R,13S,14S)-3- hydroxy-10,13...

Synonyms: AG-D-37582, CHEBI:27486, NSC-15467, KST-1A0788, NSC15467, ...

Tagawa, N. et al., Suryawanshi, S. et al., Kobayashi, Y. et al., Leathem, J.H. et al., Tagawa, N. et al.

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High impact information on NSC 15467

Pregnenolone use by corpora lutea was sharply increased in aging rats but no change occurred with 16-dehydropregnenolone [1].
We have investigated the serum concentration of 16-dehydropregnenolone (3 beta-hydroxy-5,16-pregnadien-20-one) 3-sulfate (16-DHPS) in the umbilical artery (U.A.), umbilical vein (U.V.) and maternal vein (M.V.) to discover the origin of 16-DHPS [2].
Studies on steroids in fetuses and neonates: identification of 16-dehydropregnenolone in the circulation of pre-term neonates [3].

Analytical, diagnostic and therapeutic context of NSC 15467

Development of an enzyme immunoassay for serum 16-dehydropregnenolone [4].
A sensitive and selective HPLC/ESI-MS/MS assay for the simultaneous quantification of 16-dehydropregnenolone and its major metabolites in rabbit plasma [5].

References

Ovarian delta-5-3-beta-hydroxysteroid dehydrogenase in aging rats. Leathem, J.H., Murono, E.P. Fertil. Steril. (1975) [Pubmed]
16-Dehydropregnenolone 3-sulfate, its source and metabolism in the feto-placental unit. Tagawa, N., Kusuda, S., Kobayashi, Y. Biol. Pharm. Bull. (1999) [Pubmed]
Studies on steroids in fetuses and neonates: identification of 16-dehydropregnenolone in the circulation of pre-term neonates. Kobayashi, Y., Tagawa, N., Saiki, K., Watanabe, F. Biol. Pharm. Bull. (1994) [Pubmed]
Development of an enzyme immunoassay for serum 16-dehydropregnenolone. Tagawa, N., Saiki, K., Kobayashi, Y. Biol. Pharm. Bull. (2001) [Pubmed]
A sensitive and selective HPLC/ESI-MS/MS assay for the simultaneous quantification of 16-dehydropregnenolone and its major metabolites in rabbit plasma. Suryawanshi, S., Singh, S.K., Gupta, R.C. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. (2006) [Pubmed]

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