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MeSH Review

Umbilical Arteries

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Disease relevance of Umbilical Arteries


Psychiatry related information on Umbilical Arteries


High impact information on Umbilical Arteries


Chemical compound and disease context of Umbilical Arteries


Biological context of Umbilical Arteries


Anatomical context of Umbilical Arteries


Associations of Umbilical Arteries with chemical compounds

  • Diminished prostacyclin formation in umbilical arteries of babies born to women who smoke [26].
  • It appears that there are in the umbilical artery (and probably in other tissues also) at least two separate mechanisms for control of cGMP synthesis that are influenced differently by Ca++- and O2-linked processes [27].
  • Certain agonist analogues and a selective antagonist of the chemotactic action of f-Met-Leu-Phe behaved correspondingly as agonists and antagonist of the contractile effect on umbilical artery [23].
  • The defective deposition of platelets from eight patients onto human umbilical artery subendothelium was increased but not normalized by cryoprecipitate and was not significantly affected by DDAVP or saline [28].
  • Analysis of plasma norepinephrine (NE) concentrations in umbilical artery and vein from infants of diabetic and nondiabetic mothers revealed high plasma NE values in those of diabetic mothers [29].

Gene context of Umbilical Arteries


Analytical, diagnostic and therapeutic context of Umbilical Arteries


  1. Single film retrograde umbilical aortography in the diagnosis of hypoplastic left heart syndrome with aortic atresia. Rosengart, R., Jarmakani, J.M., Emmanouilides, G.C. Circulation (1976) [Pubmed]
  2. Gene dosage-dependent effects of the Hoxa-13 and Hoxd-13 mutations on morphogenesis of the terminal parts of the digestive and urogenital tracts. Warot, X., Fromental-Ramain, C., Fraulob, V., Chambon, P., Dollé, P. Development (1997) [Pubmed]
  3. Melatonin protects against oxidized low-density lipoprotein-induced inhibition of nitric oxide production in human umbilical artery. Wakatsuki, A., Okatani, Y., Ikenoue, N., Shinohara, K., Watanabe, K., Fukaya, T. J. Pineal Res. (2001) [Pubmed]
  4. A comparative analysis of glycosaminoglycans from human umbilical arteries in normal subjects and in pathological conditions affecting pregnancy. Cardoso, L.E., Erlich, R.B., Rudge, M.C., Peraçoli, J.C., Mourão, P.A. Lab. Invest. (1992) [Pubmed]
  5. Contractile responses of the human umbilical artery from pregnancies complicated by intrauterine growth retardation. Templeton, A.G., Kingdom, J.C., Whittle, M.J., McGrath, J.C. Placenta (1993) [Pubmed]
  6. Lower serum osteocalcin levels in pregnant drug users and their newborns at the time of delivery. Rico, H., Costales, C., Cabranes, J.A., Escudero, M. Obstetrics and gynecology. (1990) [Pubmed]
  7. Oxygen promotes contraction by endothelin-1 in human umbilical artery. Bodelsson, G., Laursen, M., Stjernquist, M. Hum. Reprod. (1996) [Pubmed]
  8. Interleukin 1 activates soluble guanylate cyclase in human vascular smooth muscle cells through a novel nitric oxide-independent pathway. Beasley, D., McGuiggin, M. J. Exp. Med. (1994) [Pubmed]
  9. 15-Hydroxy-5,8,11,13-eicosatetraenoic acid inhibits human vascular cyclooxygenase. Potential role in diabetic vascular disease. Setty, B.N., Stuart, M.J. J. Clin. Invest. (1986) [Pubmed]
  10. Guanosine 3',5'-monophosphate and adenosine 3',5'-monophosphate content of human umbilical artery. Clyman, R.I., Sandler, J.A., Manganiello, V.C., Vaughan, M. J. Clin. Invest. (1975) [Pubmed]
  11. Venous and hepatic vascular responses to indomethacin and prostaglandin E1 in the fetal lamb. Paulick, R.P., Meyers, R.L., Rudolph, C.D., Rudolph, A.M. Am. J. Obstet. Gynecol. (1990) [Pubmed]
  12. Fetal hypertension induced by norepinephrine infusion and umbilical artery flow velocity waveforms in fetal sheep. van Huisseling, H., Muijsers, G.J., de Haan, J., Hasaart, T.H. Am. J. Obstet. Gynecol. (1991) [Pubmed]
  13. The vasodilatory effects of hydralazine, nicardipine, nitroglycerin, and fenoldopam in the human umbilical artery. Sato, N., Tanaka, K.A., Szlam, F., Tsuda, A., Arias, M.E., Levy, J.H. Anesth. Analg. (2003) [Pubmed]
  14. Meperidine for dystocia during the first stage of labor: A randomized controlled trial. Sosa, C.G., Balaguer, E., Alonso, J.G., Panizza, R., Laborde, A., Berrondo, C. Am. J. Obstet. Gynecol. (2004) [Pubmed]
  15. Correlation between umbilical artery resistance index, 6 ketoprostaglandin F1 alpha and thromboxane B2 in the fetoplacental compartment in patients with pregnancy induced hypertension. Mahmoud, T.Z., Bjornsson, S., Kelly, R.W., Calder, A.A. Prostaglandins (1993) [Pubmed]
  16. Effect of antenatal betamethasone administration on placental vascular resistance. Wallace, E.M., Baker, L.S. Lancet (1999) [Pubmed]
  17. Platelet-derived growth factor induces c-fms and scavenger receptor genes in vascular smooth muscle cells. Inaba, T., Gotoda, T., Shimano, H., Shimada, M., Harada, K., Kozaki, K., Watanabe, Y., Hoh, E., Motoyoshi, K., Yazaki, Y. J. Biol. Chem. (1992) [Pubmed]
  18. The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo. Azcoitia, V., Aracil, M., Martínez-A, C., Torres, M. Dev. Biol. (2005) [Pubmed]
  19. Melatonin suppresses homocysteine enhancement of serotonin-induced vasoconstriction in the human umbilical artery. Okatani, Y., Wakatsuki, A., Reiter, R.J. J. Pineal Res. (2001) [Pubmed]
  20. Responses of fetal ovine systemic and umbilical arteries to angiotensin II. Segar, J.L., Barna, T.J., Acarregui, M.J., Lamb, F.S. Pediatr. Res. (2001) [Pubmed]
  21. Reduced prostacyclin production by cultured endothelial cells from umbilical arteries of babies born to women who smoke. Busacca, M., Dejana, E., Balconi, G., Olivieri, S., Pietra, A., Vergara-Dauden, M., de Gaetano, G. Lancet (1982) [Pubmed]
  22. Inhibition of vascular smooth muscle cell growth by inhibition of fibronectin matrix assembly. Mercurius, K.O., Morla, A.O. Circ. Res. (1998) [Pubmed]
  23. Contractile effect of the chemotactic factors f-Met-Leu-Phe and C5a on the human isolated umbilical artery. Role of cyclooxygenase products and tissue macrophages. Marceau, F., deBlois, D., Laplante, C., Petitclerc, E., Pelletier, G., Grose, J.H., Hugli, T.E. Circ. Res. (1990) [Pubmed]
  24. Cbfa2 is required for the formation of intra-aortic hematopoietic clusters. North, T., Gu, T.L., Stacy, T., Wang, Q., Howard, L., Binder, M., Marín-Padilla, M., Speck, N.A. Development (1999) [Pubmed]
  25. Compensation by fetal erythrocytes of plasma glucose changes in rats. Guarner, V., Alvarez-Buylla, R. Diabetes (1990) [Pubmed]
  26. Diminished prostacyclin formation in umbilical arteries of babies born to women who smoke. Dadak, C., Leithner, C., Sinzinger, H., Silberbauer, K. Lancet (1981) [Pubmed]
  27. Oxygen and cyclic nucleotides in human umbilical artery. Clyman, R.I., Blacksin, A.S., Manganiello, V.C., Vaughan, M. Proc. Natl. Acad. Sci. U.S.A. (1975) [Pubmed]
  28. DDAVP shortens the prolonged bleeding times of patients with severe von Willebrand disease treated with cryoprecipitate. Evidence for a mechanism of action independent of released von Willebrand factor. Cattaneo, M., Moia, M., Delle Valle, P., Castellana, P., Mannucci, P.M. Blood (1989) [Pubmed]
  29. High plasma norepinephrine concentrations at birth in infants of diabetic mothers. Young, J.B., Cohen, W.R., Rappaport, E.B., Landsberg, L. Diabetes (1979) [Pubmed]
  30. Expression of the CD34 gene in vascular endothelial cells. Fina, L., Molgaard, H.V., Robertson, D., Bradley, N.J., Monaghan, P., Delia, D., Sutherland, D.R., Baker, M.A., Greaves, M.F. Blood (1990) [Pubmed]
  31. Characterization of endothelin receptors in the human umbilical artery and vein. Bogoni, G., Rizzi, A., Calo, G., Campobasso, C., D'Orleans-Juste, P., Regoli, D. Br. J. Pharmacol. (1996) [Pubmed]
  32. Vascular endothelial growth factor is bound in amniotic fluid and maternal serum. Vuorela-Vepsäläinen, P., Alfthan, H., Orpana, A., Alitalo, K., Stenman, U.H., Halmesmäki, E. Hum. Reprod. (1999) [Pubmed]
  33. Contrasting effects of interferon gamma and interleukin 4 on responses of human vascular endothelial cells to tumour necrosis factor alpha. Paleolog, E.M., Aluri, G.R., Feldmann, M. Cytokine (1992) [Pubmed]
  34. Characterization, localization and actions of endothelins in umbilical vessels and placenta of man. Hemsén, A., Gillis, C., Larsson, O., Haegerstrand, A., Lundberg, J.M. Acta Physiol. Scand. (1991) [Pubmed]
  35. Irradiation decreases vascular prostacyclin formation with no concomitant effect on platelet thromboxane production. Allen, J.B., Sagerman, R.H., Stuart, M.J. Lancet (1981) [Pubmed]
  36. Ovine placental cortisol production. Clapp, J.F., Thabault, N.C., Hubel, C.A., McLaughlin, M.K., Auletta, F.J. Endocrinology (1982) [Pubmed]
  37. Maternal-fetal transfer of melatonin in pregnant women near term. Okatani, Y., Okamoto, K., Hayashi, K., Wakatsuki, A., Tamura, S., Sagara, Y. J. Pineal Res. (1998) [Pubmed]
  38. Surface morphology of polyvinyl chloride and silicone elastomer umbilical artery catheters by scanning electron microscopy. Clawson, C.C., Boros, S.J. Pediatrics (1978) [Pubmed]
  39. Intra-arterial infusions and intestinal necrosis in the rabbit: potential hazards of umbilical artery injections of ampicillin, glucose, and sodium bicarbonate. Book, L.S., Herbst, J.J. Pediatrics (1980) [Pubmed]
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