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Chemical Compound Review

AmbotzHAA1193     (2R)-2-methylaminopropanoic acid

Synonyms: AG-E-96044, ANW-41298, AC1Q3XJO, AK-81255, CTK1A1981, ...
 
 
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Disease relevance of N-Methylalanine

  • Cell free extracts of Pseudomonas MS previously have been shown to carry out the synthesis of a novel amino acid, N-methylalanine (Kung, H.F., and Wagner, C. (1970) Biochim. Biophys. Acta 201, 513-516) [1].
 

High impact information on N-Methylalanine

References

  1. Purification and characterization of N-methylalanine dehydrogenase. Lin, M.C., Wagner, C. J. Biol. Chem. (1975) [Pubmed]
  2. Synthesis and some pharmacological properties of oxytocin and vasopressin analogues with sarcosine or N-methyl-L-alanine in position 7. Grzonka, Z., Lammek, B., Kasprzykowski, F., Gazis, D., Schwartz, I.L. J. Med. Chem. (1983) [Pubmed]
  3. Vasopressin antagonist analogs modified at position 7. Moore, M.L., Greene, H., Huffman, W.F., Stassen, F., Stefankiewicz, J., Sulat, L., Heckman, G., Schmidt, D., Kinter, L., McDonald, J. Int. J. Pept. Protein Res. (1986) [Pubmed]
 
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