Gene Review:
cheB - chemotaxis-specific methylesterase
Escherichia coli CFT073
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Disease relevance of cheB
- It has previously been reported that the alpha-proteobacterium Azospirillum brasilense undergoes methylation-independent chemotaxis; however, a recent study revealed cheB and cheR genes in this organism [1].
High impact information on cheB
- In comparison to the wild type, the cheB, cheR, and cheBR mutants showed various altered patterns of methanol release upon exposure to attractants [1].
- We have constructed cheB, cheR, and cheBR mutants of A. brasilense and determined that the CheB and CheR proteins under study significantly influence chemotaxis and aerotaxis but are not essential for these behaviors to occur [1].
Biological context of cheB
- Second, in comparison to the wild type, cheB and cheR mutants under steady-state conditions exhibited an altered swimming bias, whereas the cheBR mutant and the che operon mutant did not [1].
References
- Role of CheB and CheR in the complex chemotactic and aerotactic pathway of Azospirillum brasilense. Stephens, B.B., Loar, S.N., Alexandre, G. J. Bacteriol. (2006) [Pubmed]
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