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Gene Review

c2511  -  transposase/IS protein

Escherichia coli CFT073

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Disease relevance of c2511


High impact information on c2511

  • This model also draws support from the finding that the IS91 transposase is related in sequence to the superfamily of rolling-circle replication proteins and the observation that IRR shows some conservation in sequence and secondary structure with the origins of replication of some rolling-circle replication plasmids [3].


  1. Role of instability in the cis action of the insertion sequence IS903 transposase. Derbyshire, K.M., Kramer, M., Grindley, N.D. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  2. Transductional instability of Tn5-induced mutations: generalized and specialized transduction of Tn5 by bacteriophage P1. Berg, C.M., Grullón, C.A., Wang, A., Whalen, W.A., Berg, D.E. Genetics (1983) [Pubmed]
  3. Differential roles of the transposon termini in IS91 transposition. Mendiola, M.V., Bernales, I., de la Cruz, F. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
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