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Gene Review:

tnpA - ORF2

Erwinia pyrifoliae Ep1/96

Chuang, D.Y. et al., Ohnuma, S. et al.

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Disease relevance of tnpA

A fragment containing ORF2 and its promoter was amplified and cloned into pBR322 and pHSG415r, and the recombinant plasmids, pBYL1 and pHYL1, were transferred into E. coli DH5 [1].
Deduction from the nucleotide sequence indicated that ORF2 encodes a protein of 99 amino acids, which showed high homology with Yersinia enterocolitica Yrp, a regulator of enterotoxin (Y-ST) production; Escherichia coli host factor 1, required for Qbeta-replicase; and Azorhizobium caulinodans NrfA, required for the expression of nifA [1].

High impact information on tnpA

This sequence specifies two open reading frames, ORF-1 and ORF-2 [2].
ORF2 was designated brg, bacteriocin regulator gene [1].

References

Identification and cloning of an Erwinia carotovora subsp. carotovora bacteriocin regulator gene by insertional mutagenesis. Chuang, D.Y., Kyeremeh, A.G., Gunji, Y., Takahara, Y., Ehara, Y., Kikumoto, T. J. Bacteriol. (1999) [Pubmed]
Archaebacterial ether-linked lipid biosynthetic gene. Expression cloning, sequencing, and characterization of geranylgeranyl-diphosphate synthase. Ohnuma, S., Suzuki, M., Nishino, T. J. Biol. Chem. (1994) [Pubmed]

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