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Gene Review

BY367451  -  cDNA sequence, BY367451

Mus musculus

Synonyms: Atxn8os, Klhl1as, Sca8
 
 
 
 
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High impact information on Klhl1as

  • We found that the mouse Klhl1as RNA is not spliced and terminates in a polyadenylation site in the Klhl1 promoter region, whereas both the present and previous work show that human KLHL1AS is highly variably spliced into processed transcripts that contain up to six exons [1].
  • We have now identified the promoter region for the KLHL1-antisense ( KLHL1AS) RNA and report that a Klhl1as transcript is present in the mouse as well [1].
  • Mouse Klhl1as transcript was detected in RNA isolated from the cerebellum and from total adult brain and total fetal tissue, and at a low level in testis and ovary [1].

References

  1. The KLHL1-antisense transcript ( KLHL1AS) is evolutionarily conserved. Benzow, K.A., Koob, M.D. Mamm. Genome (2002) [Pubmed]
 
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