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Gene Review: 

Tsil  -  thymus specific insertion locus

Mus musculus

 
 
 
 
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Disease relevance of Tsil

  • A YAC that contains both Tsil and the Pim2 locus, previously shown to be involved in progression of T-cell lymphoma, was isolated [1].
 

High impact information on Tsil

  • The region flanking the transgene insertion site was isolated and made it possible to map the preintegration locus, hereafter called Tsil (for thymus-specific integration locus) on chromosome 17 between D17Rp11e and Ras12-3 [1].
 

Biological context of Tsil

References

  1. Genomic structure and precise mapping of a thymic regulatory region on mouse chromosome 17 revealed by a c-myc transgene insertion. Lavenu, A., Roland, J., Poirier, C., Cazenave, P., Babinet, C., Morello, D. Genomics (1996) [Pubmed]
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