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MeSH Review

Regulatory Sequences, Nucleic Acid

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Disease relevance of Regulatory Sequences, Nucleic Acid


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Biological context of Regulatory Sequences, Nucleic Acid


Anatomical context of Regulatory Sequences, Nucleic Acid

  • Comparison of Hoxb-1 regulatory regions from different vertebrates identified three related sequence motifs critical for rhombomere 4 (r4) expression in the hindbrain [26].
  • We previously showed that the regulatory region that is included suffices to promote the accumulation of CAT mRNA in transgenic S. purpuratus embryos, on the same developmental schedule and in the same embryonic region, the aboral ectoderm, in which the CyIIIa actin gene is normally expressed (Flytzanis et al. 1987; Hough-Evans et al. 1987) [27].
  • Previous studies have demonstrated that 181 bp of 5' flanking DNA from the AChR delta-subunit gene are sufficient to confer synapse-specific transcription in transgenic mice and NRG responsiveness in cultured muscle cells, but the critical sequences within this cis-acting regulatory region have not been identified [28].
  • Our results support a model whereby transcription factors such as NFAT1, which are nonselectively induced in antigen-stimulated T cells, gain access to cytokine regulatory regions only in the appropriate subset of differentiated T cells in vivo [29].
  • Skeletal muscle differentiation is initiated by the transcription factor MyoD, which binds directly to the regulatory regions of genes expressed during skeletal muscle differentiation and initiates chromatin remodeling at specific promoters [30].

Associations of Regulatory Sequences, Nucleic Acid with chemical compounds


Gene context of Regulatory Sequences, Nucleic Acid


Analytical, diagnostic and therapeutic context of Regulatory Sequences, Nucleic Acid


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