Gene Review:
SUPT16H - suppressor of Ty 16 homolog (S. cerevisiae)
Homo sapiens
Synonyms:
CDC68, Chromatin-specific transcription elongation factor 140 kDa subunit, FACT, FACT 140 kDa subunit, FACT complex subunit SPT16, ...
- Functional interaction of general transcription initiation factor TFIIE with general chromatin factor SPT16/CDC68. Kang, S.W., Kuzuhara, T., Horikoshi, M. Genes Cells (2000)
- Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. Pavri, R., Zhu, B., Li, G., Trojer, P., Mandal, S., Shilatifard, A., Reinberg, D. Cell. (2006)
- The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins. Orphanides, G., Wu, W.H., Lane, W.S., Hampsey, M., Reinberg, D. Nature. (1999)
- FACT facilitates transcription-dependent nucleosome alteration. Belotserkovskaya, R., Oh, S., Bondarenko, V.A., Orphanides, G., Studitsky, V.M., Reinberg, D. Science. (2003)
- FACT-mediated exchange of histone variant H2AX regulated by phosphorylation of H2AX and ADP-ribosylation of Spt16. Heo, K., Kim, H., Choi, S.H., Choi, J., Kim, K., Gu, J., Lieber, M.R., Yang, A.S., An, W. Mol. Cell. (2008)
- Modulation of nucleosome-binding activity of FACT by poly(ADP-ribosyl)ation. Huang, J.Y., Chen, W.H., Chang, Y.L., Wang, H.T., Chuang, W.T., Lee, S.C. Nucleic. Acids. Res. (2006)