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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

dre4  -  CG1828 gene product from transcript CG1828-RB

Drosophila melanogaster

Synonyms: CG1828, DRE4/dSPT16, Dmel\CG1828, FACT complex subunit spt16, Facilitates chromatin transcription complex subunit SPT16, ...
 
 
 
 
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High impact information on dre4

  • We postulate that the dre4 gene is required for ecdysteroid production at multiple stages of Drosophila development and that the pathologies observed in dre4 mutants reflect developmental consequences of ecdysteroid deficiency [1].
  • Loss-of-function mutations of the dre4 gene of Drosophila melanogaster caused stage-specific developmental arrest, the stages of arrest coinciding with periods of ecdysteroid (molting hormone) regulated development [1].

References

  1. Developmental arrest and ecdysteroid deficiency resulting from mutations at the dre4 locus of Drosophila. Sliter, T.J., Gilbert, L.I. Genetics (1992) [Pubmed]
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