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Gene Review:

Rapop2 - radiation-induced apoptosis 2

Mus musculus

Mori, N. et al., Mori, N. et al.

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High impact information on Rapop2

Apoptosis susceptibility genes on mouse chromosome 9 (Rapop2) and chromosome 3 (Rapop3) [1].
Although these two loci may be identical to Rapop1 and Rapop2, they affect apoptosis in colon in a way different from that in thymus [2].

Biological context of Rapop2

In the present study, the analysis of F2 crosses between the resistant RC strain CcS-8 and the susceptible strain BALB/cHeA or the highly susceptible RC strain CsS-10 demonstrated two additional apoptosis susceptibility genes, Rapop2 and Rapop3, located in the proximal region of chromosome 9 and the telomeric region of chromosome 3, respectively [1].

References

Apoptosis susceptibility genes on mouse chromosome 9 (Rapop2) and chromosome 3 (Rapop3). Mori, N., Okumoto, M., Hart, A.A., Demant, P. Genomics (1995) [Pubmed]
Genetics of susceptibility to radiation-induced apoptosis in colon: two loci on chromosomes 9 and 16. Mori, N., van Wezel, T., van der Valk, M., Yamate, J., Sakuma, S., Okumoto, M., Demant, P. Mamm. Genome (1998) [Pubmed]

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