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Gene Review

NACC1  -  nucleus accumbens associated 1, BEN and...

Homo sapiens

Synonyms: BEND8, BTB/POZ domain-containing protein 14B, BTBD14B, BTBD30, NAC-1, ...
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Disease relevance of NACC1

  • Our findings suggest that NAC-1 may play an important role in cervical carcinomas; moreover, these findings provide a rationale for future development of NAC-1-based therapy for cervical carcinomas that overexpress this candidate oncogene [1].

Associations of NACC1 with chemical compounds


Regulatory relationships of NACC1


  1. Expression of the bric-a-brac tramtrack broad complex protein NAC-1 in cervical carcinomas seems to correlate with poorer prognosis. Yeasmin, S., Nakayama, K., Ishibashi, M., Katagiri, A., Iida, K., Purwana, I.N., Nakayama, N., Miyazaki, K. Clin. Cancer Res. (2008) [Pubmed]
  2. A BTB/POZ gene, NAC-1, a tumor recurrence-associated gene, as a potential target for Taxol resistance in ovarian cancer. Ishibashi, M., Nakayama, K., Yeasmin, S., Katagiri, A., Iida, K., Nakayama, N., Fukumoto, M., Miyazaki, K. Clin. Cancer Res. (2008) [Pubmed]
  3. NAC-1 controls cell growth and survival by repressing transcription of Gadd45GIP1, a candidate tumor suppressor. Nakayama, K., Nakayama, N., Wang, T.L., Shih, I. Cancer Res. (2007) [Pubmed]
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