Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

Chrne - cholinergic receptor, nicotinic, epsilon...

Mus musculus

Synonyms: AChrepsilon, Acetylcholine receptor subunit epsilon, Acre, nAChRE

Lu, G. et al., Dan, I. et al.

Dan, Watanabe, Kajikawa, Ishida, Pandey, Kusumi,

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Chrne

Inhibition of CDK2 activity with either the specific CDK2 inhibitory peptide Tat-LFG or by RNA interference abolished neuregulin-induced AChRepsilon expression [1].
The switch from the fetal AChRgamma subunit to the adult-type AChRepsilon is required for synapse maturation and the neuromuscular junction [1].
CHRNE codes for the epsilon subunit of the nicotinic acetylcholine receptor (AChRepsilon) whereas MINK encodes a serine/threonine kinase belonging to the GCK family [2].

References

Novel role for cyclin-dependent kinase 2 in neuregulin-induced acetylcholine receptor epsilon subunit expression in differentiated myotubes. Lu, G., Seta, K.A., Millhorn, D.E. J. Biol. Chem. (2005) [Pubmed]
Overlapping of MINK and CHRNE gene loci in the course of mammalian evolution. Dan, I., Watanabe, N.M., Kajikawa, E., Ishida, T., Pandey, A., Kusumi, A. Nucleic Acids Res. (2002) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

CHRNE	Bos taurus
CHRNE	Canis lupus familiaris
CHRNE	Homo sapiens
CHRNE	Macaca mulatta
CHRNE	Pan troglodytes
Chrne	Rattus norvegicus
chrne	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share