Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

GPRASP2 - G protein-coupled receptor associated...

Homo sapiens

Synonyms: FLJ37327, G-protein coupled receptor-associated sorting protein 2, GASP-2, GASP2

Horn, S.C. et al., Simonin, F. et al.

Simonin, Karcher, Boeuf, Matifas, Kieffer,

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High impact information on GPRASP2

Finally, we show that GASP-1 is a member of a novel family comprising at least 10 members, whose genes are clustered on chromosome X. Another member of the family, GASP-2, also interacts with the carboxyl-terminal tail of several GPCRs [1].
Huntingtin interacts with the receptor sorting family protein GASP2 [2].
As the GASP protein family plays a role in G protein-coupled receptor sorting, our data suggest that htt might influence receptor trafficking via the interaction with GASP2 [2].

References

Identification of a novel family of G protein-coupled receptor associated sorting proteins. Simonin, F., Karcher, P., Boeuf, J.J., Matifas, A., Kieffer, B.L. J. Neurochem. (2004) [Pubmed]
Huntingtin interacts with the receptor sorting family protein GASP2. Horn, S.C., Lalowski, M., Goehler, H., Dröge, A., Wanker, E.E., Stelzl, U. Journal of neural transmission (Vienna, Austria : 1996) (2006) [Pubmed]

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