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Gene Review

GPRASP1  -  G protein-coupled receptor associated...

Homo sapiens

Synonyms: G-protein coupled receptor-associated sorting protein 1, GASP, GASP-1, GASP1, KIAA0443
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Disease relevance of GPRASP1

  • Help! (Puff! Puff!) I have an emergency! (Gasp]). The emergency management of hyperventilation [1].

High impact information on GPRASP1


Biological context of GPRASP1

  • These concerted evolution events occurred within and between genes from three separate protein families ('brain-expressed X-linked' [BEX], WWbp5-like X-linked [WEX] and G-protein-coupled receptor-associated sorting protein [GASP]), which often are expressed in mammalian brains and associated with receptor mediated signalling and apoptosis [6].


  1. Help! (Puff! Puff!) I have an emergency! (Gasp]). The emergency management of hyperventilation. Sandvik, J.R. Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association. (1977) [Pubmed]
  2. A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP). Heydorn, A., Søndergaard, B.P., Ersbøll, B., Holst, B., Nielsen, F.C., Haft, C.R., Whistler, J., Schwartz, T.W. J. Biol. Chem. (2004) [Pubmed]
  3. Regulation of myostatin in vivo by growth and differentiation factor-associated serum protein-1: a novel protein with protease inhibitor and follistatin domains. Hill, J.J., Qiu, Y., Hewick, R.M., Wolfman, N.M. Mol. Endocrinol. (2003) [Pubmed]
  4. Identification of a novel family of G protein-coupled receptor associated sorting proteins. Simonin, F., Karcher, P., Boeuf, J.J., Matifas, A., Kieffer, B.L. J. Neurochem. (2004) [Pubmed]
  5. Differential gene expression in Perillus bioculatus nymphs fed a suboptimal artificial diet. Yocum, G.D., Coudron, T.A., Brandt, S.L. J. Insect Physiol. (2006) [Pubmed]
  6. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. Winter, E.E., Ponting, C.P. BMC Evol. Biol. (2005) [Pubmed]
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