Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Gripap1 - GRIP1 associated protein 1

Rattus norvegicus

Synonyms: GRASP-1, GRIP1-associated protein 1, Grasp1

Rickhag, M. et al., Feng, W. et al., Ye, B. et al.

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High impact information on Gripap1

In addition, the subcellular distribution of both AMPA receptors and GRASP-1 was rapidly regulated by the activation of NMDA receptors [1].
NMR titration experiments show that GRIP1 PDZ7 binds to GRASP-1 via this hydrophobic surface [2].
K-means cluster analysis revealed two distinct biphasic gene expression patterns that contained 44 genes (including 18 immediate early genes), involved in cell signaling and plasticity (i.e. MAP2K7, Sprouty2, Irs-2, Homer1, GPRC5B, Grasp) [3].

Associations of Gripap1 with chemical compounds

The interaction between GRIP1 PDZ7 and a Ras guanine nucleotide exchange factor, GRASP-1, regulates synaptic distribution of AMPA receptors [2].

References

GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex. Ye, B., Liao, D., Zhang, X., Zhang, P., Dong, H., Huganir, R.L. Neuron (2000) [Pubmed]
PDZ7 of glutamate receptor interacting protein binds to its target via a novel hydrophobic surface area. Feng, W., Fan, J.S., Jiang, M., Shi, Y.W., Zhang, M. J. Biol. Chem. (2002) [Pubmed]
Comprehensive regional and temporal gene expression profiling of the rat brain during the first 24 h after experimental stroke identifies dynamic ischemia-induced gene expression patterns, and reveals a biphasic activation of genes in surviving tissue. Rickhag, M., Wieloch, T., Gidö, G., Elmér, E., Krogh, M., Murray, J., Lohr, S., Bitter, H., Chin, D.J., von Schack, D., Shamloo, M., Nikolich, K. J. Neurochem. (2006) [Pubmed]

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