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Gene Review

SSX2IP  -  synovial sarcoma, X breakpoint 2...

Homo sapiens

Synonyms: ADIP, Afadin DIL domain-interacting protein, Afadin-and alpha-actinin-binding protein, KIAA0923, SSX2-interacting protein
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High impact information on SSX2IP

  • Likewise, the SSX2IP protein was found to be colocalizing with SSX2 in the nucleus [1].
  • By doing so, two novel human proteins were detected: RAB3IP, the human homolog of an interactor of the Ras-like GTPase Rab3A; and a novel protein, SSX2IP [1].
  • RT-PCR analysis indicated that we had identified three antigens which were expressed in patient bone marrow (BM) and peripheral blood (PB) but not in normal donor samples (PASD1, SSX2IP, and GRINL1A) [2].
  • Analysis of the obtained magnetic-dipole interaction constants (Adip) shows that fluorine 2p and xenon 5p atomic orbitals make a major contribution to the spin density distribution in XeF*. Both relativistic and nonrelativistic calculations give close magnetic-dipole interaction constants, which are in agreement with the measured values [3].

Physical interactions of SSX2IP

  • Further analysis of deletion mutants showed that both RAB3IP and SSX2IP interact with the N-terminal moiety of the SSX2 protein [1].


  1. The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP. de Bruijn, D.R., dos Santos, N.R., Kater-Baats, E., Thijssen, J., van den Berk, L., Stap, J., Balemans, M., Schepens, M., Merkx, G., van Kessel, A.G. Genes Chromosomes Cancer (2002) [Pubmed]
  2. Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia. Guinn, B.A., Bland, E.A., Lodi, U., Liggins, A.P., Tobal, K., Petters, S., Wells, J.W., Banham, A.H., Mufti, G.J. Biochem. Biophys. Res. Commun. (2005) [Pubmed]
  3. High-resolution electron spin resonance spectroscopy of XeF* in solid argon. The hyperfine structure constants as a probe of relativistic effects in the chemical bonding properties of a heavy noble gas atom. Misochko, E.Y., Akimov, A.V., Goldschleger, I.U., Tyurin, D.A., Laikov, D.N. The Journal of chemical physics. (2005) [Pubmed]
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