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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Pfkfb3  -  6-phosphofructo-2-kinase/fructose-2,6...

Rattus norvegicus

Synonyms: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3, 6PF-2-K/Fru-2,6-P2ase 3, 6PF-2-K/Fru-2,6-P2ase brain-type isozyme, PFK/FBPase 3, RB2K
 
 
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High impact information on Pfkfb3

  • In the present study, we quantified these splice variants in various tissues using a RNAse protection assay and found a tissue-specific pattern of alternative splicing of the RB2K gene [1].
  • We have reported the occurrence of eight splice variants of rat brain fructose 6-phosphate 2-kinase/fructose 2,6-bisphosphatase (RB2K) [1].
  • These results suggest that distinct RB2K isoforms could be involved in regulation of glycolysis in a tissue-specific manner [1].

References

  1. Tissue-specific alternative splicing of rat brain fructose 6-phosphate 2-kinase/fructose 2,6-bisphosphatase. Watanabe, F., Furuya, E. FEBS Lett. (1999) [Pubmed]
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