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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

AP1S1  -  adaptor-related protein complex 1, sigma 1...

Homo sapiens

Synonyms: AP-1 complex subunit sigma-1A, AP19, Adaptor protein complex AP-1 subunit sigma-1A, Adaptor-related protein complex 1 subunit sigma-1A, CLAPS1, ...
 
 
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High impact information on AP1S1

  • A sequence comparison of rat brain AP17 with mouse brain AP19 demonstrates that the small chains are highly related [1].
  • In addition, we localized genes for two other components of the AP-1 adaptor, i.e., the medium (AP47) and small (AP19) subunits, to chromosomes 19 and 7, respectively [2].
  • The availability of this sequence as well as a previous AP19 in a plant allows one to propose that specific AP complexes exist in plants in the Golgi complex and in the plasma membrane [3].
  • Five minutes after discontinuing halothane, in increase in arterial blood pressure was recorded (AP 19 +/- 6 mmHg), which was accompanied by an increase in the unitary activities (n = 8.43 +/- 23%) [4].

References

  1. AP17 and AP19, the mammalian small chains of the clathrin-associated protein complexes show homology to Yap17p, their putative homolog in yeast. Kirchhausen, T., Davis, A.C., Frucht, S., Greco, B.O., Payne, G.S., Tubb, B. J. Biol. Chem. (1991) [Pubmed]
  2. Cloning, expression pattern, and chromosomal assignment to 16q23 of the human gamma-adaptin gene (ADTG). Peyrard, M., Parveneh, S., Lagercrantz, S., Ekman, M., Fransson, I., Sahlén, S., Dumanski, J.P. Genomics (1998) [Pubmed]
  3. Characterization of the sequence coding for the clathrin coat assembly protein AP17 (sigma2) associated with the plasma membrane from Zea mays and constitutive expression of its gene. Roca, R., Stiefel, V., Puigdomènech, P. Gene (1998) [Pubmed]
  4. Increased activity of bulbospinal cardiovascular neurons in the rat rostral ventrolateral medulla upon emergence from anaesthesia. Frugière, A., Quintin, L., Barillot, J.C. J. Auton. Nerv. Syst. (1996) [Pubmed]
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