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Gene Review:

cylM - cylM protein

Enterococcus faecalis V583

Poeta, P. et al., Jurkovic, D. et al., Bittencourt de Marques, E. et al., Gilmore, M.S. et al., P??rez-Pulido, R. et al.

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High impact information on cylM

Four open reading frames are required for expression of the cytolysin precursor (cylLL, cylLS, cylM, and cylB) [1].
PCR was also used for assessment of presence of vanA and vanB genes and virulence determinants gelE, agg and cytolysin genes namely: cylL(L), cylL(S), cylM, cylB and cylA [2].
Other presumed virulence genes (agg, gelE, cylM, cylA and efaA(fs)) were not detected [3].
In addition, the presence of genes of the gelE-fsrABC locus and of the cyl operon (cylL(L), cylL(S), cylA, cylB and cylM) were studied by polymerase chain reaction and correlated with gelatinase and beta-haemolysis production, respectively [4].

Analytical, diagnostic and therapeutic context of cylM

A total of 95 E. faecalis strains were investigated for the presence of nine virulence genes including aggA, cylA, cylB, cylM, eep, efaA, enlA, esp and gelE by using PCR [5].

References

Genetic structure of the Enterococcus faecalis plasmid pAD1-encoded cytolytic toxin system and its relationship to lantibiotic determinants. Gilmore, M.S., Segarra, R.A., Booth, M.C., Bogie, C.P., Hall, L.R., Clewell, D.B. J. Bacteriol. (1994) [Pubmed]
Identification and characterization of enterococci from bryndza cheese. Jurkovic, D., Krizková, L., Dusinský, R., Belicová, A., Sojka, M., Krajcovic, J., Ebringer, L. Lett. Appl. Microbiol. (2006) [Pubmed]
Safety and potential risks of enterococci isolated from traditional fermented capers. P??rez-Pulido, R., Abriouel, H., Ben Omar, N., Lucas, R., Mart??nez-Ca??amero, M., G??lvez, A. Food Chem. Toxicol. (2006) [Pubmed]
Phenotypic and genotypic study of gelatinase and beta-haemolysis activities in faecal enterococci of poultry in Portugal. Poeta, P., Costa, D., Klibi, N., Rodrigues, J., Torres, C. J. Vet. Med. B Infect. Dis. Vet. Public Health (2006) [Pubmed]
Occurrence of virulence-associated genes in clinical Enterococcus faecalis strains isolated in Londrina, Brazil. Bittencourt de Marques, E., Suzart, S. J. Med. Microbiol. (2004) [Pubmed]

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