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Gene Review

vapE  -  VapE

Rhodococcus equi

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High impact information on vapE

  • Notably, the CFS contained the previously characterized proteins VapC, VapD, and VapE, which are encoded by genes on the R. equi virulence plasmid [1].
  • In this report we show that the ORF13-protein coded by the virulence associated plasmid of R. equi is clearly homologous to VapE [2].
  • A theoretical extension of the sequence of ORF13 by the introduction of a single nucleotide yields a translated amino acid sequence that is highly homologous to VapE and other members of the Vap family [2].


  1. Rhodococcus equi secreted antigens are immunogenic and stimulate a type 1 recall response in the lungs of horses immune to R. equi infection. Kohler, A.K., Stone, D.M., Hines, M.T., Byrne, B.A., Alperin, D.C., Norton, L.K., Hines, S.A. Infect. Immun. (2003) [Pubmed]
  2. VapI, a new member of the Rhodococcus equi Vap family. Polidori, M., Haas, A. Antonie Van Leeuwenhoek (2006) [Pubmed]
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