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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Col9a3  -  collagen, type IX, alpha 3

Mus musculus

Synonyms: AV006866
 
 
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High impact information on Col9a3

  • Here we show that the deficiency in alpha1(IX) chains leads to a functional knock-out of all polypeptides of collagen IX, whereas the Col9a2 and Col9a3 genes were normally transcribed [1].
  • Tescalcin, a novel gene encoding a putative EF-hand Ca(2+)-binding protein, Col9a3, and renin are expressed in the mouse testis during the early stages of gonadal differentiation [2].
  • These studies showed Col9a3 and Col2a1 to be expressed in Sertoli cells within the developing testis cords [3].

References

  1. Absence of the alpha1(IX) chain leads to a functional knock-out of the entire collagen IX protein in mice. Hagg, R., Hedbom, E., Möllers, U., Aszódi, A., Fässler, R., Bruckner, P. J. Biol. Chem. (1997) [Pubmed]
  2. Tescalcin, a novel gene encoding a putative EF-hand Ca(2+)-binding protein, Col9a3, and renin are expressed in the mouse testis during the early stages of gonadal differentiation. Perera, E.M., Martin, H., Seeherunvong, T., Kos, L., Hughes, I.A., Hawkins, J.R., Berkovitz, G.D. Endocrinology (2001) [Pubmed]
  3. Type II and type IX collagen transcript isoforms are expressed during mouse testis development. McClive, P.J., Sinclair, A.H. Biol. Reprod. (2003) [Pubmed]
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