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Gene Review

UROC1  -  urocanate hydratase 1

Homo sapiens

Synonyms: FLJ31300, HMFN0320, Imidazolonepropionate hydrolase, Urocanase, Urocanate hydratase
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Disease relevance of UROC1

  • Urocanase (EC from Pseudomonas putida was crystallized after removing one of the seven free thiol groups [1].

High impact information on UROC1


  1. Structure and action of urocanase. Kessler, D., Rétey, J., Schulz, G.E. J. Mol. Biol. (2004) [Pubmed]
  2. Thioglycolate, competitive inhibitor of urocanase. Hug, D.H., O'Donnell, P.S., Hunter, J.K. Biochem. Biophys. Res. Commun. (1978) [Pubmed]
  3. Biochemical study of malnutrition. Part VI: Histidine and its metabolites. Antener, I., Verwilghen, A.M., Van Geert, C., Mauron, J. International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition. (1983) [Pubmed]
  4. A liver urocanase deficiency. Kalafatic, Z., Lipovac, K., Jezerinac, Z., Juretic, D., Dumic, M., Zurga, B., Res, L. Metab. Clin. Exp. (1980) [Pubmed]
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