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Gene Review

Erbb3  -  v-erb-b2 erythroblastic leukemia viral...

Mus musculus

Synonyms: C76256, Erbb-3, Erbb3r, Glial growth factor receptor, HER3, ...
 
 
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Disease relevance of Erbb3

  • Moreover, transfer of non-tumor-specific T cells in combination with the fusion proteins, induced the eradication of established Her-2, Her-3, and Her-4 expressing tumor cells in SCID mice [1].
 

High impact information on Erbb3

 

Analytical, diagnostic and therapeutic context of Erbb3

References

  1. Anti-Her-2/neu-IL-2 or heregulin-IL-2 fusions proteins redirect non-tumor specific CTL to the tumor site for tumor eradication. Lustgarten, J. Cancer Immunol. Immunother. (2003) [Pubmed]
  2. c-erbB-3: a nuclear protein in mammary epithelial cells. Offterdinger, M., Schöfer, C., Weipoltshammer, K., Grunt, T.W. J. Cell Biol. (2002) [Pubmed]
  3. Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland. Yang, Y., Spitzer, E., Meyer, D., Sachs, M., Niemann, C., Hartmann, G., Weidner, K.M., Birchmeier, C., Birchmeier, W. J. Cell Biol. (1995) [Pubmed]
 
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