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Gene Review

Ercc3  -  excision repair cross-complementing rodent...

Mus musculus

Synonyms: BTF2 p89, Basic transcription factor 2 89 kDa subunit, DNA excision repair protein ERCC-3, DNA repair protein complementing XP-B cells, Ercc-3, ...
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Disease relevance of Ercc3

  • Defects in the XPB, XPD, and XPG genes can result in three different syndromes, xeroderma pigmentosum, Cockayne syndrome, or trichothiodystrophy, depending on the specific mutation involved [1].


  1. Disorders of DNA replication and repair. Auerbach, A.D., Verlander, P.C. Curr. Opin. Pediatr. (1997) [Pubmed]
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