Gene Review:
hay - haywire
Drosophila melanogaster
Synonyms:
ATP-dependent DNA helicase hay, CG8019, DNA excision repair protein haywire, DhR25, DhXPB, ...
- A Drosophila model for xeroderma pigmentosum and Cockayne's syndrome: haywire encodes the fly homolog of ERCC3, a human excision repair gene. Mounkes, L.C., Jones, R.S., Liang, B.C., Gelbart, W., Fuller, M.T. Cell (1992)
- Cdk7 is essential for mitosis and for in vivo Cdk-activating kinase activity. Larochelle, S., Pandur, J., Fisher, R.P., Salz, H.K., Suter, B. Genes Dev. (1998)
- Interacting genes that affect microtubule function: the nc2 allele of the haywire locus fails to complement mutations in the testis-specific beta-tubulin gene of Drosophila. Regan, C.L., Fuller, M.T. Genes Dev. (1988)
- T-loop phosphorylation stabilizes the CDK7-cyclin H-MAT1 complex in vivo and regulates its CTD kinase activity. Larochelle, S., Chen, J., Knights, R., Pandur, J., Morcillo, P., Erdjument-Bromage, H., Tempst, P., Suter, B., Fisher, R.P. EMBO J. (2001)
- Cdk7 is required for full activation of Drosophila heat shock genes and RNA polymerase II phosphorylation in vivo. Schwartz, B.E., Larochelle, S., Suter, B., Lis, J.T. Mol. Cell. Biol. (2003)
- RNA polymerase II 140wimp mutant and mutations in the TFIIH subunit XPB differentially affect homeotic gene expression in Drosophila. Gutiérrez, L., Merino, C., Vázquez, M., Reynaud, E., Zurita, M. Genesis (2004)
- Xpd/Ercc2 regulates CAK activity and mitotic progression. Chen, J., Larochelle, S., Li, X., Suter, B. Nature (2003)
- TFIIH trafficking and its nuclear assembly during early Drosophila embryo development. Aguilar-Fuentes, J., Valadez-Graham, V., Reynaud, E., Zurita, M. J. Cell. Sci. (2006)
- Dominant-negative mutants reveal a role for the Cdk7 kinase at the mid-blastula transition in Drosophila embryos. Leclerc, V., Raisin, S., Léopold, P. EMBO J. (2000)
- DNA repair and transcriptional deficiencies caused by mutations in the Drosophila p52 subunit of TFIIH generate developmental defects and chromosome fragility. Fregoso, M., Lainé, J.P., Aguilar-Fuentes, J., Mocquet, V., Reynaud, E., Coin, F., Egly, J.M., Zurita, M. Mol. Cell. Biol. (2007)
- Molecular characterization of mutant alleles of the DNA repair/basal transcription factor haywire/ERCC3 in Drosophila. Mounkes, L.C., Fuller, M.T. Genetics (1999)
- Interacting genes that affect microtubule function in Drosophila melanogaster: two classes of mutation revert the failure to complement between haync2 and mutations in tubulin genes. Regan, C.L., Fuller, M.T. Genetics (1990)