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Gene Review:

polyprotein - polyprotein

Onion yellow dwarf virus

Attasart, P. et al., Chen, J. et al., Gargouri-Bouzid, R. et al., Stenger, D.C. et al., Waltermann, A. et al.

Stenger, Hein, French,

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Disease relevance of polyprotein

Phylogenetic analysis of the amino acid sequences of the polyprotein showed that OYDV is distantly related to Pea seed-borne mosaic virus and the potyviruses of grasses and cereals [1].
Nested deletion analysis of Wheat streak mosaic virus HC-Pro: Mapping of domains affecting polyprotein processing and eriophyid mite transmission [2].
The RNA genome of Plum pox virus (PPV) encodes one large polyprotein that is subsequently cleaved into mature viral proteins [3].

High impact information on polyprotein

The NIa protease forms the nuclear inclusion body A and acts as the major protease in the cleavage of the viral polyprotein into functional proteins [4].
The viral genome is 10,323 nucleotides (nts) long and contains an ORF encoding polyprotein 3,343 amino acids (aa) long, flanked with 5'- and 3'-non-coding regions (NCRs) of 85 and 206 nts, respectively [5].

References

Sequence analysis demonstrates that Onion yellow dwarf virus isolates from China contain a P3 region much larger than other potyviruses. Chen, J., Adams, M.J., Zheng, H.Y., Chen, J.P. Arch. Virol. (2003) [Pubmed]
Nested deletion analysis of Wheat streak mosaic virus HC-Pro: Mapping of domains affecting polyprotein processing and eriophyid mite transmission. Stenger, D.C., Hein, G.L., French, R. Virology (2006) [Pubmed]
Detection of 6K1 as a mature protein of 6 kDa in plum pox virus-infected Nicotiana benthamiana. Waltermann, A., Maiss, E. J. Gen. Virol. (2006) [Pubmed]
PVY-Resistant Transgenic Potato Plants Expressing an Anti-NIa Protein scFv Antibody. Gargouri-Bouzid, R., Jaoua, L., Rouis, S., Saídi, M.N., Bouaziz, D., Ellouz, R. Mol. Biotechnol. (2006) [Pubmed]
Nucleotide sequence of a Thai isolate of Papaya ringspot virus type W. Attasart, P., Charoensilp, G., Kertbundit, S., Panyim, S., Juricek, M. Acta Virol. (2002) [Pubmed]

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