Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

PABPC5 - poly(A) binding protein, cytoplasmic 5

Homo sapiens

Synonyms: PABP-5, PABP5, Poly(A)-binding protein 5, Polyadenylate-binding protein 5

Blanco, P. et al.

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High impact information on PABPC5

A novel poly(A)-binding protein gene (PABPC5) maps to an X-specific subinterval in the Xq21.3/Yp11.2 homology block of the human sex chromosomes [1].
PABPC5 has 73% nucleotide identity with PABPC4 over 1801 bp of the ORF [1].
The genomic structure of PABPC5 covers 4061 bp of an uninterrupted open reading frame (ORF) and a 5'UTR spanning across two exons and associated with a CpG island; the potential 382-amino-acid protein contains four RNA recognition motif domains [1].

Analytical, diagnostic and therapeutic context of PABPC5

RT-PCR indicates that PABPC5 is expressed in fetal brain and in a range of adult tissues [1].

References

A novel poly(A)-binding protein gene (PABPC5) maps to an X-specific subinterval in the Xq21.3/Yp11.2 homology block of the human sex chromosomes. Blanco, P., Sargent, C.A., Boucher, C.A., Howell, G., Ross, M., Affara, N.A. Genomics (2001) [Pubmed]

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